4okh: Difference between revisions
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''' | ==Crystal structure of calpain-3 penta-EF-hand domain== | ||
<StructureSection load='4okh' size='340' side='right' caption='[[4okh]], [[Resolution|resolution]] 2.45Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4okh]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OKH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OKH FirstGlance]. <br> | |||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PEU:2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL'>PEU</scene><br> | |||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calpain-3 Calpain-3], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.54 3.4.22.54] </span></td></tr> | |||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4okh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4okh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4okh RCSB], [http://www.ebi.ac.uk/pdbsum/4okh PDBsum]</span></td></tr> | |||
<table> | |||
== Disease == | |||
[[http://www.uniprot.org/uniprot/CAN3_HUMAN CAN3_HUMAN]] Autosomal recessive limb girdle muscular dystrophy type 2A. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/CAN3_HUMAN CAN3_HUMAN]] Calcium-regulated non-lysosomal thiol-protease. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Calpain-3]] | |||
[[Category: Allingham, J S.]] | |||
[[Category: Campbell, R L.]] | |||
[[Category: Davies, P L.]] | |||
[[Category: Partha, S Karunan.]] | |||
[[Category: Ravulapalli, R.]] | |||
[[Category: Calcium-binding]] | |||
[[Category: Ef-hand]] | |||
[[Category: Hydrolase]] | |||
Revision as of 10:07, 28 May 2014
Crystal structure of calpain-3 penta-EF-hand domain
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