3s02: Difference between revisions

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[[~~Image~~:~~3s02~~.~~jpg~~|~~left~~|~~200px~~]]

==The crystal structure of the periplasmic domain of Helicobacter pylori MotB (residues 103-256)==

== Structural highlights ==

<table><tr><td colspan='2'>[[3s02]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S02 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3S02 FirstGlance]. <br>

<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HP_0816, motB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=210 Helicobacter pylori])</td></tr>

<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3s02 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s02 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3s02 RCSB], [http://www.ebi.ac.uk/pdbsum/3s02 PDBsum]</span></td></tr>

<table>

== Publication Abstract from PubMed ==

Bacterial flagella are driven by an ion influx through the peptidoglycan (PG)-tethered MotA/MotB stator. Stator precomplexes assemble in the membrane and remain inactive until they incorporate into the motor, upon which MotA/MotB changes conformation. The nature of this change and the mechanism of inhibition of the PG-binding and ion-conducting activities of the precomplexes are unknown. Here, the structural analysis of a series of N-terminally truncated MotB fragments is presented, the mechanism of inhibition by the linker is identified and the structural basis for the formation of the PG-binding-competent open-channel MotA/MotB conformation via a mechanism that entails linker unfolding and rotational displacement of MotB transmembrane helices is uncovered.

~~<!--~~

Role of the MotB linker in the assembly and activation of the bacterial flagellar motor.,O'Neill J, Xie M, Hijnen M, Roujeinikova A Acta Crystallogr D Biol Crystallogr. 2011 Dec;67(Pt 12):1009-16. Epub 2011 Nov 5. PMID:22120737<ref>PMID:22120737</ref>

~~The line below this paragraph~~, ~~containing "STRUCTURE_3s02"~~, ~~creates the "Structure Box" on the page~~.

~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)

~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~

~~or leave the SCENE parameter empty for the default display~~.

-->

~~{{STRUCTURE_3s02| PDB=3s02 | SCENE= }}~~

~~===The crystal structure~~ of the ~~periplasmic domain~~ of ~~Helicobacter pylori MotB (residues 103-256)===~~

From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>

</div>

==See Also==

~~<!--~~

*[[Chemotaxis protein|Chemotaxis protein]]

~~The line below this paragraph, {{ABSTRACT_PUBMED_22120737}}, adds the Publication Abstract to the page~~

== References ==

~~(as it appears on PubMed at http://www.pubmed.gov), where 22120737 is the PubMed ID number.~~

~~-->~~

__TOC__

~~{{ABSTRACT_PUBMED_22120737}}~~

</StructureSection>

==~~About this Structure~~==

[[~~3s02~~]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S02 OCA].

==~~Reference~~==

<~~ref group="xtra">PMID:022120737<~~/~~ref~~><~~ref group="xtra">PMID:018540076</ref><references group="xtra"~~/>

[[Category: Helicobacter pylori]]

[[Category: Roujeinikova, A R.]]

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@@ Line 1: / Line 1: @@
-[[Image:3s02.jpg|left|200px]]
+==The crystal structure of the periplasmic domain of Helicobacter pylori MotB (residues 103-256)==
+<StructureSection load='3s02' size='340' side='right' caption='[[3s02]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3s02]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S02 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3S02 FirstGlance]. <br>
+</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3s03|3s03]], [[3s06|3s06]], [[3s0h|3s0h]], [[3s0w|3s0w]], [[3s0y|3s0y]]</td></tr>
+<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HP_0816, motB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=210 Helicobacter pylori])</td></tr>
+<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3s02 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s02 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3s02 RCSB], [http://www.ebi.ac.uk/pdbsum/3s02 PDBsum]</span></td></tr>
+<table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Bacterial flagella are driven by an ion influx through the peptidoglycan (PG)-tethered MotA/MotB stator. Stator precomplexes assemble in the membrane and remain inactive until they incorporate into the motor, upon which MotA/MotB changes conformation. The nature of this change and the mechanism of inhibition of the PG-binding and ion-conducting activities of the precomplexes are unknown. Here, the structural analysis of a series of N-terminally truncated MotB fragments is presented, the mechanism of inhibition by the linker is identified and the structural basis for the formation of the PG-binding-competent open-channel MotA/MotB conformation via a mechanism that entails linker unfolding and rotational displacement of MotB transmembrane helices is uncovered.
-<!--
+Role of the MotB linker in the assembly and activation of the bacterial flagellar motor.,O'Neill J, Xie M, Hijnen M, Roujeinikova A Acta Crystallogr D Biol Crystallogr. 2011 Dec;67(Pt 12):1009-16. Epub 2011 Nov 5. PMID:22120737<ref>PMID:22120737</ref>
-The line below this paragraph, containing "STRUCTURE_3s02", creates the "Structure Box" on the page.
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-or leave the SCENE parameter empty for the default display.
--->
-{{STRUCTURE_3s02|  PDB=3s02  |  SCENE=  }}
-===The crystal structure of the periplasmic domain of Helicobacter pylori MotB (residues 103-256)===
+From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
+</div>
+==See Also==
-<!--
+*[[Chemotaxis protein|Chemotaxis protein]]
-The line below this paragraph, {{ABSTRACT_PUBMED_22120737}}, adds the Publication Abstract to the page
+== References ==
-(as it appears on PubMed at http://www.pubmed.gov), where 22120737 is the PubMed ID number.
+<references/>
--->
+__TOC__
-{{ABSTRACT_PUBMED_22120737}}
+</StructureSection>
-==About this Structure==
-[[3s02]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S02 OCA].
-==Reference==
-<ref group="xtra">PMID:022120737</ref><ref group="xtra">PMID:018540076</ref><references group="xtra"/>
 [[Category: Helicobacter pylori]]
 [[Category: Roujeinikova, A R.]]