1ay0: Difference between revisions

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[[Image:1ay0.jpg|left|200px]]<br /><applet load="1ay0" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1ay0.jpg|left|200px]]
caption="1ay0, resolution 2.6&Aring;" />
 
'''IDENTIFICATION OF CATALYTICALLY IMPORTANT RESIDUES IN YEAST TRANSKETOLASE'''<br />
{{Structure
|PDB= 1ay0 |SIZE=350|CAPTION= <scene name='initialview01'>1ay0</scene>, resolution 2.6&Aring;
|SITE= <scene name='pdbsite=NUL:Active+Site+Mutant'>NUL</scene>
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=TPP:THIAMINE DIPHOSPHATE'>TPP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Transketolase Transketolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.2.1.1 2.2.1.1]
|GENE= TKL1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])
}}
 
'''IDENTIFICATION OF CATALYTICALLY IMPORTANT RESIDUES IN YEAST TRANSKETOLASE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1AY0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=TPP:'>TPP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Transketolase Transketolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.2.1.1 2.2.1.1] Known structural/functional Site: <scene name='pdbsite=NUL:Active+Site+Mutant'>NUL</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AY0 OCA].  
1AY0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AY0 OCA].  


==Reference==
==Reference==
Identification of catalytically important residues in yeast transketolase., Wikner C, Nilsson U, Meshalkina L, Udekwu C, Lindqvist Y, Schneider G, Biochemistry. 1997 Dec 16;36(50):15643-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9398292 9398292]
Identification of catalytically important residues in yeast transketolase., Wikner C, Nilsson U, Meshalkina L, Udekwu C, Lindqvist Y, Schneider G, Biochemistry. 1997 Dec 16;36(50):15643-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9398292 9398292]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: CA]]
[[Category: CA]]
[[Category: TPP]]
[[Category: TPP]]
[[Category: ketone residues]]
[[Category: ketone residue]]
[[Category: mutant]]
[[Category: mutant]]
[[Category: thiamin diphosphate]]
[[Category: thiamin diphosphate]]
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[[Category: transketolase mechanism]]
[[Category: transketolase mechanism]]


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