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[[Image:3say.jpg|left|200px]]
==Crystal structure of human glycogen synthase kinase 3 beta (GSK3b) in complex with inhibitor 142==
<StructureSection load='3say' size='340' side='right' caption='[[3say]], [[Resolution|resolution]] 2.23&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3say]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SAY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SAY FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=OFT:(3Z)-N,N-DIETHYL-3-[(3E)-3-(HYDROXYIMINO)-1,3-DIHYDRO-2H-INDOL-2-YLIDENE]-2-OXO-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE'>OFT</scene><br>
<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GSK3B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/[Tau_protein]_kinase [Tau protein] kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.26 2.7.11.26] </span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3say FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3say OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3say RCSB], [http://www.ebi.ac.uk/pdbsum/3say PDBsum]</span></td></tr>
<table>


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==See Also==
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*[[Glycogen synthase kinase 3|Glycogen synthase kinase 3]]
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{{STRUCTURE_3say|  PDB=3say  |  SCENE= }}
 
===Crystal structure of human glycogen synthase kinase 3 beta (GSK3b) in complex with inhibitor 142===
 
 
==About this Structure==
[[3say]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SAY OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Barker, J J.]]
[[Category: Barker, J J.]]

Revision as of 05:29, 5 June 2014

Crystal structure of human glycogen synthase kinase 3 beta (GSK3b) in complex with inhibitor 142

3say, resolution 2.23Å

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