3t3a: Difference between revisions

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[[~~Image~~:~~3t3a~~.~~png~~|~~left~~|~~200px~~]]

==Crystal structure of H107R mutant of extracellular domain of mouse receptor NKR-P1A==

== Structural highlights ==

<table><tr><td colspan='2'>[[3t3a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T3A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T3A FirstGlance]. <br>

</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>

<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3m9z|3m9z]]</td></tr>

<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Klrb1a, Ly55, Ly55a, Nkrp1a ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>

<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t3a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t3a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3t3a RCSB], [http://www.ebi.ac.uk/pdbsum/3t3a PDBsum]</span></td></tr>

<table>

== Publication Abstract from PubMed ==

The structure of the H107R variant of the extracellular domain of the mouse natural killer cell receptor NKR-P1A has been determined by X-ray diffraction at 2.3 A resolution from a merohedrally twinned crystal. Unlike the structure of the wild-type receptor in space group I4(1)22 with a single chain per asymmetric unit, the crystals of the variant belonged to space group I4(1) with a dimer in the asymmetric unit. Different degrees of merohedral twinning were detected in five data sets collected from different crystals. The mutation does not have a significant impact on the overall structure, but led to the binding of an additional phosphate ion at the interface of the molecules.

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Structure of the H107R variant of the extracellular domain of mouse NKR-P1A at 2.3 A resolution.,Kolenko P, Rozbesky D, Vanek O, Bezouska K, Hasek J, Dohnalek J Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Dec 1;67(Pt 12):1519-23., Epub 2011 Nov 30. PMID:22139156<ref>PMID:22139156</ref>

~~The line below this paragraph~~, ~~containing "STRUCTURE_3t3a"~~, ~~creates the "Structure Box" on the page~~.

~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet)~~

~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded~~),

~~or leave the SCENE parameter empty for the default display~~.

-->

~~{{STRUCTURE_3t3a| PDB=3t3a | SCENE= }}~~

~~===Crystal structure of H107R mutant of extracellular domain~~ of ~~mouse receptor NKR-P1A===~~

From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>

</div>

== References ==

~~<!--~~

~~The line below this paragraph, {{ABSTRACT_PUBMED_22139156}}, adds the Publication Abstract to~~ the ~~page~~

__TOC__

~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 22139156 is the PubMed ID number~~.

</StructureSection>

-->

~~{{ABSTRACT_PUBMED_22139156}}~~

~~==About this Structure==~~

~~[[3t3a]] is a 2 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T3A OCA].~~

==~~Reference~~==

<~~ref group="xtra">PMID:022139156<~~/~~ref~~><~~references group="xtra"~~/>

[[Category: Mus musculus]]

[[Category: Bezouska, K.]]

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@@ Line 1: / Line 1: @@
-[[Image:3t3a.png|left|200px]]
+==Crystal structure of H107R mutant of extracellular domain of mouse receptor NKR-P1A==
+<StructureSection load='3t3a' size='340' side='right' caption='[[3t3a]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3t3a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T3A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T3A FirstGlance]. <br>
+</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
+<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3m9z|3m9z]]</td></tr>
+<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Klrb1a, Ly55, Ly55a, Nkrp1a ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
+<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t3a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t3a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3t3a RCSB], [http://www.ebi.ac.uk/pdbsum/3t3a PDBsum]</span></td></tr>
+<table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+The structure of the H107R variant of the extracellular domain of the mouse natural killer cell receptor NKR-P1A has been determined by X-ray diffraction at 2.3 A resolution from a merohedrally twinned crystal. Unlike the structure of the wild-type receptor in space group I4(1)22 with a single chain per asymmetric unit, the crystals of the variant belonged to space group I4(1) with a dimer in the asymmetric unit. Different degrees of merohedral twinning were detected in five data sets collected from different crystals. The mutation does not have a significant impact on the overall structure, but led to the binding of an additional phosphate ion at the interface of the molecules.
-<!--
+Structure of the H107R variant of the extracellular domain of mouse NKR-P1A at 2.3 A resolution.,Kolenko P, Rozbesky D, Vanek O, Bezouska K, Hasek J, Dohnalek J Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Dec 1;67(Pt 12):1519-23., Epub 2011 Nov 30. PMID:22139156<ref>PMID:22139156</ref>
-The line below this paragraph, containing "STRUCTURE_3t3a", creates the "Structure Box" on the page.
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-or leave the SCENE parameter empty for the default display.
--->
-{{STRUCTURE_3t3a|  PDB=3t3a  |  SCENE=  }}
-===Crystal structure of H107R mutant of extracellular domain of mouse receptor NKR-P1A===
+From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
+</div>
+== References ==
-<!--
+<references/>
-The line below this paragraph, {{ABSTRACT_PUBMED_22139156}}, adds the Publication Abstract to the page
+__TOC__
-(as it appears on PubMed at http://www.pubmed.gov), where 22139156 is the PubMed ID number.
+</StructureSection>
--->
-{{ABSTRACT_PUBMED_22139156}}
-==About this Structure==
-[[3t3a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T3A OCA].
-==Reference==
-<ref group="xtra">PMID:022139156</ref><references group="xtra"/>
 [[Category: Mus musculus]]
 [[Category: Bezouska, K.]]