1b4e: Difference between revisions

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[[Image:1b4e.jpg|left|200px]]<br /><applet load="1b4e" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1b4e.jpg|left|200px]]
caption="1b4e, resolution 2.0&Aring;" />
 
'''X-RAY STRUCTURE OF 5-AMINOLEVULINIC ACID DEHYDRATASE COMPLEXED WITH THE INHIBITOR LEVULINIC ACID.'''<br />
{{Structure
|PDB= 1b4e |SIZE=350|CAPTION= <scene name='initialview01'>1b4e</scene>, resolution 2.0&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=LEA:LEVULINIC+ACID'>LEA</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Porphobilinogen_synthase Porphobilinogen synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.24 4.2.1.24]
|GENE= HEM2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
}}
 
'''X-RAY STRUCTURE OF 5-AMINOLEVULINIC ACID DEHYDRATASE COMPLEXED WITH THE INHIBITOR LEVULINIC ACID.'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1B4E is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=LEA:'>LEA</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Porphobilinogen_synthase Porphobilinogen synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.24 4.2.1.24] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B4E OCA].  
1B4E is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B4E OCA].  


==Reference==
==Reference==
X-ray structure of 5-aminolevulinic acid dehydratase from Escherichia coli complexed with the inhibitor levulinic acid at 2.0 A resolution., Erskine PT, Norton E, Cooper JB, Lambert R, Coker A, Lewis G, Spencer P, Sarwar M, Wood SP, Warren MJ, Shoolingin-Jordan PM, Biochemistry. 1999 Apr 6;38(14):4266-76. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10194344 10194344]
X-ray structure of 5-aminolevulinic acid dehydratase from Escherichia coli complexed with the inhibitor levulinic acid at 2.0 A resolution., Erskine PT, Norton E, Cooper JB, Lambert R, Coker A, Lewis G, Spencer P, Sarwar M, Wood SP, Warren MJ, Shoolingin-Jordan PM, Biochemistry. 1999 Apr 6;38(14):4266-76. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10194344 10194344]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Porphobilinogen synthase]]
[[Category: Porphobilinogen synthase]]
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[[Category: dehydratase]]
[[Category: dehydratase]]


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