1b9d: Difference between revisions

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[[Image:1b9d.gif|left|200px]]<br /><applet load="1b9d" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1b9d.gif|left|200px]]
caption="1b9d, resolution 1.7&Aring;" />
 
'''MOBILITY OF AN HIV-1 INTEGRASE ACTIVE SITE LOOP IS CORRELATED WITH CATALYTIC ACTIVITY'''<br />
{{Structure
|PDB= 1b9d |SIZE=350|CAPTION= <scene name='initialview01'>1b9d</scene>, resolution 1.7&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene> and <scene name='pdbligand=SO4:SULFATE ION'>SO4</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49]
|GENE=
}}
 
'''MOBILITY OF AN HIV-1 INTEGRASE ACTIVE SITE LOOP IS CORRELATED WITH CATALYTIC ACTIVITY'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1B9D is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_1_(isolate_12) Human immunodeficiency virus type 1 (isolate 12)] with <scene name='pdbligand=CAC:'>CAC</scene> and <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B9D OCA].  
1B9D is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_1_(isolate_12) Human immunodeficiency virus type 1 (isolate 12)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B9D OCA].  


==Reference==
==Reference==
The mobility of an HIV-1 integrase active site loop is correlated with catalytic activity., Greenwald J, Le V, Butler SL, Bushman FD, Choe S, Biochemistry. 1999 Jul 13;38(28):8892-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10413462 10413462]
The mobility of an HIV-1 integrase active site loop is correlated with catalytic activity., Greenwald J, Le V, Butler SL, Bushman FD, Choe S, Biochemistry. 1999 Jul 13;38(28):8892-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10413462 10413462]
[[Category: Human immunodeficiency virus type 1 (isolate 12)]]
[[Category: Human immunodeficiency virus type 1 (isolate 12)]]
[[Category: RNA-directed DNA polymerase]]
[[Category: RNA-directed DNA polymerase]]
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[[Category: dna integration]]
[[Category: dna integration]]


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