1bx6: Difference between revisions

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[[Image:1bx6.gif|left|200px]]<br /><applet load="1bx6" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1bx6.gif|left|200px]]
caption="1bx6, resolution 2.1&Aring;" />
 
'''CRYSTAL STRUCTURE OF THE POTENT NATURAL PRODUCT INHIBITOR BALANOL IN COMPLEX WITH THE CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE'''<br />
{{Structure
|PDB= 1bx6 |SIZE=350|CAPTION= <scene name='initialview01'>1bx6</scene>, resolution 2.1&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=BA1:BALANOL'>BA1</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1]
|GENE=
}}
 
'''CRYSTAL STRUCTURE OF THE POTENT NATURAL PRODUCT INHIBITOR BALANOL IN COMPLEX WITH THE CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1BX6 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=BA1:'>BA1</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BX6 OCA].  
1BX6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BX6 OCA].  


==Reference==
==Reference==
Crystal structure of the potent natural product inhibitor balanol in complex with the catalytic subunit of cAMP-dependent protein kinase., Narayana N, Diller TC, Koide K, Bunnage ME, Nicolaou KC, Brunton LL, Xuong NH, Ten Eyck LF, Taylor SS, Biochemistry. 1999 Feb 23;38(8):2367-76. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10029530 10029530]
Crystal structure of the potent natural product inhibitor balanol in complex with the catalytic subunit of cAMP-dependent protein kinase., Narayana N, Diller TC, Koide K, Bunnage ME, Nicolaou KC, Brunton LL, Xuong NH, Ten Eyck LF, Taylor SS, Biochemistry. 1999 Feb 23;38(8):2367-76. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10029530 10029530]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: BA1]]
[[Category: BA1]]
[[Category: balanol]]
[[Category: balanol]]
[[Category: conformational changes]]
[[Category: conformational change]]
[[Category: crystal structure]]
[[Category: crystal structure]]
[[Category: inhibition]]
[[Category: inhibition]]
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[[Category: serine/threonine-protein kinase]]
[[Category: serine/threonine-protein kinase]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:00:01 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:16:57 2008''