1c8m: Difference between revisions

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[[Image:1c8m.gif|left|200px]]<br /><applet load="1c8m" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1c8m.gif|left|200px]]
caption="1c8m, resolution 2.8&Aring;" />
 
'''REFINED CRYSTAL STRUCTURE OF HUMAN RHINOVIRUS 16 COMPLEXED WITH VP63843 (PLECONARIL), AN ANTI-PICORNAVIRAL DRUG CURRENTLY IN CLINICAL TRIALS'''<br />
{{Structure
|PDB= 1c8m |SIZE=350|CAPTION= <scene name='initialview01'>1c8m</scene>, resolution 2.8&Aring;
|SITE= <scene name='pdbsite=ION:Putative+Zn+Binding+Site+On+Icosahedral+Five-Fold+Axis.+...'>ION</scene>, <scene name='pdbsite=POC:An+Antiviral+Compound+Is+Found+In+A+Pocket+Of+Vp1'>POC</scene> and <scene name='pdbsite=RNA:RNA+Observed+Interacting+w.+These+Residues+On+The+Interi+...'>RNA</scene>
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=W11:3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE'>W11</scene>
|ACTIVITY=
|GENE=
}}
 
'''REFINED CRYSTAL STRUCTURE OF HUMAN RHINOVIRUS 16 COMPLEXED WITH VP63843 (PLECONARIL), AN ANTI-PICORNAVIRAL DRUG CURRENTLY IN CLINICAL TRIALS'''
 


==About this Structure==
==About this Structure==
1C8M is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Human_rhinovirus_14 Human rhinovirus 14] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=W11:'>W11</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. The following page contains interesting information on the relation of 1C8M with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb20_1.html Poliovirus and Rhinovirus]]. Known structural/functional Sites: <scene name='pdbsite=ION:Putative+Zn+Binding+Site+On+Icosahedral+Five-Fold+Axis.+...'>ION</scene>, <scene name='pdbsite=POC:An+Antiviral+Compound+Is+Found+In+A+Pocket+Of+Vp1'>POC</scene> and <scene name='pdbsite=RNA:RNA+Observed+Interacting+w.+These+Residues+On+The+Interi+...'>RNA</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C8M OCA].  
1C8M is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Human_rhinovirus_14 Human rhinovirus 14]. The following page contains interesting information on the relation of 1C8M with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb20_1.html Poliovirus and Rhinovirus]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C8M OCA].  
[[Category: Human rhinovirus 14]]
[[Category: Human rhinovirus 14]]
[[Category: Poliovirus and Rhinovirus]]
[[Category: Poliovirus and Rhinovirus]]
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[[Category: win compound]]
[[Category: win compound]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:03:32 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:21:15 2008''