4npv: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Crystal structure of human PDE1B bound to inhibitor 7A (6,7,8-trimethoxy-N-(pentan-3-yl)quinazolin-4-amine)==

~~The entry~~ 4npv is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4npv]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NPV OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NPV FirstGlance].

~~Authors~~: ~~Pandit~~, J., Evdomikov, A., Mansour, M., Simons, S.

</td></tr><tr><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=0NK:6,7,8-TRIMETHOXY-N-(PENTAN-3-YL)QUINAZOLIN-4-AMINE'>0NK</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>

<tr><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[4npw|4npw]]</td></tr>

~~Description~~:

<tr><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/3',5'-cyclic-nucleotide_phosphodiesterase 3',5'-cyclic-nucleotide phosphodiesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.4.17 3.1.4.17] </td></tr>

<tr><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4npv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4npv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4npv RCSB], [http://www.ebi.ac.uk/pdbsum/4npv PDBsum]</td></tr>

<table>

__TOC__

</StructureSection>

[[Category: 3',5'-cyclic-nucleotide phosphodiesterase]]

[[Category: Evdomikov, A.]]

[[Category: Mansour, M.]]

[[Category: Pandit, J.]]

[[Category: Simons, S.]]

[[Category: Hydrolase]]

[[Category: Hydrolase-hydrolase inhibitor complex]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Crystal structure of human PDE1B bound to inhibitor 7A (6,7,8-trimethoxy-N-(pentan-3-yl)quinazolin-4-amine)==
+<StructureSection load='4npv' size='340' side='right' caption='[[4npv]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-The entry 4npv is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4npv]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NPV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NPV FirstGlance]. <br>
-Authors: Pandit, J., Evdomikov, A., Mansour, M., Simons, S.
+</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0NK:6,7,8-TRIMETHOXY-N-(PENTAN-3-YL)QUINAZOLIN-4-AMINE'>0NK</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
+<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4npw|4npw]]</td></tr>
-Description:
+<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3',5'-cyclic-nucleotide_phosphodiesterase 3',5'-cyclic-nucleotide phosphodiesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.4.17 3.1.4.17] </span></td></tr>
+<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4npv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4npv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4npv RCSB], [http://www.ebi.ac.uk/pdbsum/4npv PDBsum]</span></td></tr>
+<table>
+__TOC__
+</StructureSection>
+[[Category: 3',5'-cyclic-nucleotide phosphodiesterase]]
+[[Category: Evdomikov, A.]]
+[[Category: Mansour, M.]]
+[[Category: Pandit, J.]]
+[[Category: Simons, S.]]
+[[Category: Hydrolase]]
+[[Category: Hydrolase-hydrolase inhibitor complex]]