4txc: Difference between revisions

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'''Unreleased structure'''
==Crystal Structure of DAPK1 kinase domain in complex with a small molecule inhibitor==
 
<StructureSection load='4txc' size='340' side='right' caption='[[4txc]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
The entry 4txc is ON HOLD
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4txc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TXC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TXC FirstGlance]. <br>
Authors: Sorrell, F.J., Krojer, T., Wilbek, T.S., Skovgaard, T., Berthelsen, J., Dixon-Clark, S., Chalk, R., Von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Stromgaard, K., Knapp, S.
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=38G:4-(3-{3-[(R)-{[2-(DIMETHYLAMINO)ETHYL]AMINO}(HYDROXY)METHYL]PHENYL}IMIDAZO[1,2-B]PYRIDAZIN-6-YL)-2-METHOXYPHENOL'>38G</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene><br>
 
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2yak|2yak]], [[4pf4|4pf4]]</td></tr>
Description: Crystal Structure of DAPK1 kinase domain in complex with a small molecule inhibitor
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4txc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4txc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4txc RCSB], [http://www.ebi.ac.uk/pdbsum/4txc PDBsum]</span></td></tr>
<table>
__TOC__
</StructureSection>
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Arrowsmith, C H.]]
[[Category: Berthelsen, J.]]
[[Category: Bountra, C.]]
[[Category: Chalk, R.]]
[[Category: Delft, F Von.]]
[[Category: Dixon-Clarke, S.]]
[[Category: Edwards, A M.]]
[[Category: Knapp, S.]]
[[Category: Krojer, T.]]
[[Category: Skovgaard, T.]]
[[Category: Sorrell, F J.]]
[[Category: Stromgaard, K.]]
[[Category: Wilbek, T S.]]
[[Category: Catalytic domain]]
[[Category: Kinase]]
[[Category: Protein binding]]
[[Category: Protein kinase]]
[[Category: Protein kinase inhibitor]]
[[Category: Protein-ligand complex]]
[[Category: Small-molecule]]
[[Category: Transferase]]

Revision as of 08:15, 23 July 2014

Crystal Structure of DAPK1 kinase domain in complex with a small molecule inhibitor

4txc, resolution 1.95Å

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