2w93: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
Line 1: Line 1:
[[Image:2w93.png|left|200px]]
==Crystal structure of the Saccharomyces cerevisiae pyruvate decarboxylase variant E477Q in complex with the surrogate pyruvamide==
 
<StructureSection load='2w93' size='340' side='right' caption='[[2w93]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
{{STRUCTURE_2w93|  PDB=2w93  |  SCENE=  }}
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2w93]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W93 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W93 FirstGlance]. <br>
===CRYSTAL STRUCTURE OF THE SACCHAROMYCES CEREVISIAE PYRUVATE DECARBOXYLASE VARIANT E477Q IN COMPLEX WITH THE SURROGATE PYRUVAMIDE===
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PY0:(1S,2S)-1-AMINO-1,2-DIHYDROXYPROPAN-1-OLATE'>PY0</scene>, <scene name='pdbligand=TPP:THIAMINE+DIPHOSPHATE'>TPP</scene><br>
 
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1qpb|1qpb]], [[1pyd|1pyd]], [[2vk8|2vk8]], [[1pvd|1pvd]], [[2vk1|2vk1]]</td></tr>
 
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyruvate_decarboxylase Pyruvate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.1 4.1.1.1] </span></td></tr>
==About this Structure==
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w93 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w93 RCSB], [http://www.ebi.ac.uk/pdbsum/2w93 PDBsum]</span></td></tr>
[[2w93]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W93 OCA].  
<table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w9/2w93_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Pyruvate decarboxylase|Pyruvate decarboxylase]]
*[[Pyruvate decarboxylase|Pyruvate decarboxylase]]
__TOC__
</StructureSection>
[[Category: Atcc 18824]]
[[Category: Pyruvate decarboxylase]]
[[Category: Pyruvate decarboxylase]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Konig, S.]]
[[Category: Konig, S.]]
[[Category: Kutter, S.]]
[[Category: Kutter, S.]]