1d6w: Difference between revisions

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[[Image:1d6w.gif|left|200px]]<br /><applet load="1d6w" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1d6w.gif|left|200px]]
caption="1d6w, resolution 2.0&Aring;" />
 
'''STRUCTURE OF THROMBIN COMPLEXED WITH SELECTIVE NON-ELECTROPHILIC INHIBITORS HAVING CYCLOHEXYL MOIETIES AT P1'''<br />
{{Structure
|PDB= 1d6w |SIZE=350|CAPTION= <scene name='initialview01'>1d6w</scene>, resolution 2.0&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=AIM:4-(4-AMINO-CYCLOHEXYLIDENE)-4H-IMIDAZOL-2-YLAMINE'>AIM</scene>, <scene name='pdbligand=HMM:5-HYDROXYMETHYL-2-METHYL-5,8-DIHYDRO-[1,2,4]TRIAZOLO[1,2-A]PYRIDAZINE-1,3-DIONE'>HMM</scene> and <scene name='pdbligand=SML:PHENYL METHYL SULFONE'>SML</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5]
|GENE=
}}
 
'''STRUCTURE OF THROMBIN COMPLEXED WITH SELECTIVE NON-ELECTROPHILIC INHIBITORS HAVING CYCLOHEXYL MOIETIES AT P1'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1D6W is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NA:'>NA</scene>, <scene name='pdbligand=AIM:'>AIM</scene>, <scene name='pdbligand=HMM:'>HMM</scene> and <scene name='pdbligand=SML:'>SML</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D6W OCA].  
1D6W is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D6W OCA].  


==Reference==
==Reference==
Structure of thrombin complexed with selective non-electrophilic inhibitors having cyclohexyl moieties at P1., Krishnan R, Mochalkin I, Arni R, Tulinsky A, Acta Crystallogr D Biol Crystallogr. 2000 Mar;56(Pt 3):294-303. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10713516 10713516]
Structure of thrombin complexed with selective non-electrophilic inhibitors having cyclohexyl moieties at P1., Krishnan R, Mochalkin I, Arni R, Tulinsky A, Acta Crystallogr D Biol Crystallogr. 2000 Mar;56(Pt 3):294-303. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10713516 10713516]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: thrombin inhibitor]]
[[Category: thrombin inhibitor]]


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