CHEM2052 Tutorial Example4: Difference between revisions
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<scene name='59/596437/Renin_catalytic_residues/1'>Renin Catalytic Residues</scene> | <scene name='59/596437/Renin_catalytic_residues/1'>Renin Catalytic Residues</scene> | ||
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== Background == | |||
In later lecture we will look at an enzyme called Renin (also known as angiotensinase). This enzyme is involved in a biological pathway leading to elevation of blood pressure, which can be beneficial in many ways. However if this process has become overactive, hypertension (high blood pressure) can result. Hypertension leads to cardiovascular disease which is the leading cause of death globally. The World Health Organisation states "An estimated 17.3 million people died from cardiovascular disease in 2008, representing 30% of all global deaths" see the following web page if you want to know more: [http://www.who.int/mediacentre/factsheets/fs317/en/]. | In later lecture we will look at an enzyme called Renin (also known as angiotensinase). This enzyme is involved in a biological pathway leading to elevation of blood pressure, which can be beneficial in many ways. However if this process has become overactive, hypertension (high blood pressure) can result. Hypertension leads to cardiovascular disease which is the leading cause of death globally. The World Health Organisation states "An estimated 17.3 million people died from cardiovascular disease in 2008, representing 30% of all global deaths" see the following web page if you want to know more: [http://www.who.int/mediacentre/factsheets/fs317/en/]. | ||
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== | == Active Site and Mechanism == | ||
== | == Inhibitors == | ||
== Structural highlights == | == Structural highlights == | ||
