1bn0: Difference between revisions

Line 1:

[[~~Image~~:1bn0.~~png|left|200px~~]]

==SL3 HAIRPIN FROM THE PACKAGING SIGNAL OF HIV-1, NMR, 11 STRUCTURES==

== Structural highlights ==

<table><tr><td colspan='2'>[[1bn0]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BN0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BN0 FirstGlance]. <br>

</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bn0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1bn0 RCSB], [http://www.ebi.ac.uk/pdbsum/1bn0 PDBsum]</span></td></tr>

<table>

== Publication Abstract from PubMed ==

An NMR-based structure is presented for a 20 mer hairpin model of the SL3 stem-loop from the HIV-1 packaging signal. The stem has an A-family structure. However, the GGAG tetraloop appears to be flexible with the second (G10) and fourth (G12) bases extruded from the normal stacking arrangement. The A-base (A11) occupies a cavity large enough for it to jump rapidly between stacking upon G9 (in the loop) and G13 (from the base-pair adjacent to the loop). The H-bonding loci of G10, A11, and G12 are unoccupied in the free RNA structure. The loop should be easily adaptable to binding by the HIV-1 nucleocapsid protein or loop receptors.

~~{{STRUCTURE_1bn0| PDB=1bn0 | SCENE= }}~~

Three-dimensional folding of an RNA hairpin required for packaging HIV-1.,Pappalardo L, Kerwood DJ, Pelczer I, Borer PN J Mol Biol. 1998 Oct 2;282(4):801-18. PMID:9743628<ref>PMID:9743628</ref>

~~===SL3 HAIRPIN FROM THE PACKAGING SIGNAL OF HIV-1~~, ~~NMR, 11 STRUCTURES===~~

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>

</div>

~~{{ABSTRACT_PUBMED_9743628}}~~

== References ==

==~~About this Structure~~==

__TOC__

~~[[1bn0]] is a 1 chain structure. Full experimental information is available from [http:~~//~~oca.weizmann.ac.il/oca-bin/ocashort?id=1BN0 OCA].~~

</StructureSection>

[[Category: Borer, P N.]]

[[Category: Kerwood, D J.]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-[[Image:1bn0.png|left|200px]]
+==SL3 HAIRPIN FROM THE PACKAGING SIGNAL OF HIV-1, NMR, 11 STRUCTURES==
+<StructureSection load='1bn0' size='340' side='right' caption='[[1bn0]], [[NMR_Ensembles_of_Models | 11 NMR models]]' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1bn0]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BN0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BN0 FirstGlance]. <br>
+</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bn0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1bn0 RCSB], [http://www.ebi.ac.uk/pdbsum/1bn0 PDBsum]</span></td></tr>
+<table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+An NMR-based structure is presented for a 20 mer hairpin model of the SL3 stem-loop from the HIV-1 packaging signal. The stem has an A-family structure. However, the GGAG tetraloop appears to be flexible with the second (G10) and fourth (G12) bases extruded from the normal stacking arrangement. The A-base (A11) occupies a cavity large enough for it to jump rapidly between stacking upon G9 (in the loop) and G13 (from the base-pair adjacent to the loop). The H-bonding loci of G10, A11, and G12 are unoccupied in the free RNA structure. The loop should be easily adaptable to binding by the HIV-1 nucleocapsid protein or loop receptors.
-{{STRUCTURE_1bn0|  PDB=1bn0  |  SCENE=  }}
+Three-dimensional folding of an RNA hairpin required for packaging HIV-1.,Pappalardo L, Kerwood DJ, Pelczer I, Borer PN J Mol Biol. 1998 Oct 2;282(4):801-18. PMID:9743628<ref>PMID:9743628</ref>
-===SL3 HAIRPIN FROM THE PACKAGING SIGNAL OF HIV-1, NMR, 11 STRUCTURES===
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
-{{ABSTRACT_PUBMED_9743628}}
+== References ==
+<references/>
-==About this Structure==
+__TOC__
-[[1bn0]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BN0 OCA].
+</StructureSection>
 [[Category: Borer, P N.]]
 [[Category: Kerwood, D J.]]