1dl8: Difference between revisions

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[[Image:1dl8.gif|left|200px]]<br /><applet load="1dl8" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1dl8.gif|left|200px]]
caption="1dl8, resolution 1.55&Aring;" />
 
'''CRYSTAL STRUCTURE OF 5-F-9-AMINO-(N-(2-DIMETHYLAMINO)ETHYL)ACRIDINE-4-CARBOXAMIDE BOUND TO D(CGTACG)2'''<br />
{{Structure
|PDB= 1dl8 |SIZE=350|CAPTION= <scene name='initialview01'>1dl8</scene>, resolution 1.55&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=DA7:5-FLUORO-9-AMINO-(N-(2-DIMETHYLAMINO)ETHYL)ACRIDINE-4-CARBOXAMIDE'>DA7</scene>
|ACTIVITY=
|GENE=
}}
 
'''CRYSTAL STRUCTURE OF 5-F-9-AMINO-(N-(2-DIMETHYLAMINO)ETHYL)ACRIDINE-4-CARBOXAMIDE BOUND TO D(CGTACG)2'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1DL8 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ] with <scene name='pdbligand=DA7:'>DA7</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DL8 OCA].  
1DL8 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DL8 OCA].  


==Reference==
==Reference==
Acridinecarboxamide topoisomerase poisons: structural and kinetic studies of the DNA complexes of 5-substituted 9-amino-(N-(2-dimethylamino)ethyl)acridine-4-carboxamides., Adams A, Guss JM, Collyer CA, Denny WA, Prakash AS, Wakelin LP, Mol Pharmacol. 2000 Sep;58(3):649-58. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10953060 10953060]
Acridinecarboxamide topoisomerase poisons: structural and kinetic studies of the DNA complexes of 5-substituted 9-amino-(N-(2-dimethylamino)ethyl)acridine-4-carboxamides., Adams A, Guss JM, Collyer CA, Denny WA, Prakash AS, Wakelin LP, Mol Pharmacol. 2000 Sep;58(3):649-58. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10953060 10953060]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Adams, A.]]
[[Category: Adams, A.]]
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[[Category: intercalation]]
[[Category: intercalation]]


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