Nucleoprotein: Difference between revisions
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'''Nucleoproteins''' (NP) are associated with DNA or RNA. NPs which contain RNA are called ribonucleoproteins (RNPs). The NP RNA-recognition motif is named RRM. The small nuclear ribonucleoproteins (snRNPs) are RNA-protein complexes which form part of the spliceosome. The heterogenous nuclear ribonucleoproteins (hnRNP) are RNA-protein complexes which associates with the splicing apparatus and prevent the folding of pre-mRNA. The images at the left and at the right correspond to one representative NP, ''i.e.'' the crystal structure of Nucleoprotein from Vesicular stomatitis Indiana virus ([[3pto]]). For homology model and multiple sequence alignment see [[User:Michael Strong/H1N1/NP]] and [[User:Michael Strong/H1N1/NP/MSA]]. | '''Nucleoproteins''' (NP) are associated with DNA or RNA. NPs which contain RNA are called ribonucleoproteins (RNPs). The NP RNA-recognition motif is named RRM. The small nuclear ribonucleoproteins (snRNPs) are RNA-protein complexes which form part of the spliceosome. The heterogenous nuclear ribonucleoproteins (hnRNP) are RNA-protein complexes which associates with the splicing apparatus and prevent the folding of pre-mRNA. The images at the left and at the right correspond to one representative NP, ''i.e.'' the crystal structure of Nucleoprotein from Vesicular stomatitis Indiana virus ([[3pto]]). For homology model and multiple sequence alignment see [[User:Michael Strong/H1N1/NP]] and [[User:Michael Strong/H1N1/NP/MSA]]. | ||
== 3D Structures of Nucleoprotein == | == 3D Structures of Nucleoprotein == | ||
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[[4k7e]] – NP C terminal – Junin virus<br /> | [[4k7e]] – NP C terminal – Junin virus<br /> | ||
''Nucleoprotein binary complex'' | |||
[[3mx2]], [[3mx5]] – LvNP + nucleotide<br /> | [[3mx2]], [[3mx5]] – LvNP + nucleotide<br /> | ||
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[[1n9r]], [[1n9s]] – y-snRNP F | [[1n9r]], [[1n9s]] – y-snRNP F | ||
''Small nuclear ribonucleoprotein binary complex'' | |||
[[3plu]], [[3plv]] – y-snRNP HINDI domain + ubiquitin-like modifier HUB1<br /> | [[3plu]], [[3plv]] – y-snRNP HINDI domain + ubiquitin-like modifier HUB1<br /> | ||
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[[2dk2]] - h-hnRNP R RRM – NMR<br /> | [[2dk2]] - h-hnRNP R RRM – NMR<br /> | ||
''Heterogenous nuclear ribonucleoprotein binary complex'' | |||
[[2kfy]], [[2kg0]], [[2kg1]] - h-hnRNP F QRRM + DNA – NMR<br /> | [[2kfy]], [[2kg0]], [[2kg1]] - h-hnRNP F QRRM + DNA – NMR<br /> | ||