Nucleoprotein: Difference between revisions

From Proteopedia
Jump to navigationJump to search
Michal Harel (talk | contribs)
No edit summary
Michal Harel (talk | contribs)
No edit summary
Line 25: Line 25:


'''Nucleoproteins''' (NP) are associated with DNA or RNA.  NPs which contain RNA are called ribonucleoproteins (RNPs).  The NP RNA-recognition motif is named RRM.  The small nuclear ribonucleoproteins (snRNPs) are RNA-protein complexes which form part of the spliceosome.  The heterogenous nuclear ribonucleoproteins (hnRNP) are RNA-protein complexes which associates with the splicing apparatus and prevent the folding of pre-mRNA. The images at the left and at the right correspond to one representative NP, ''i.e.'' the crystal structure of Nucleoprotein from Vesicular stomatitis Indiana virus ([[3pto]]).  For homology model and multiple sequence alignment see [[User:Michael Strong/H1N1/NP]] and [[User:Michael Strong/H1N1/NP/MSA]].
'''Nucleoproteins''' (NP) are associated with DNA or RNA.  NPs which contain RNA are called ribonucleoproteins (RNPs).  The NP RNA-recognition motif is named RRM.  The small nuclear ribonucleoproteins (snRNPs) are RNA-protein complexes which form part of the spliceosome.  The heterogenous nuclear ribonucleoproteins (hnRNP) are RNA-protein complexes which associates with the splicing apparatus and prevent the folding of pre-mRNA. The images at the left and at the right correspond to one representative NP, ''i.e.'' the crystal structure of Nucleoprotein from Vesicular stomatitis Indiana virus ([[3pto]]).  For homology model and multiple sequence alignment see [[User:Michael Strong/H1N1/NP]] and [[User:Michael Strong/H1N1/NP/MSA]].
{{TOC limit|limit=2}}
 
<br />
<br />
<br />
<br />
<br />
== 3D Structures of Nucleoprotein ==
== 3D Structures of Nucleoprotein ==


Line 69: Line 64:
[[4k7e]] – NP C terminal – Junin virus<br />
[[4k7e]] – NP C terminal – Junin virus<br />


===Nucleoprotein binary complex===
''Nucleoprotein binary complex''


[[3mx2]], [[3mx5]] – LvNP + nucleotide<br />
[[3mx2]], [[3mx5]] – LvNP + nucleotide<br />
Line 113: Line 108:
[[1n9r]], [[1n9s]] – y-snRNP F
[[1n9r]], [[1n9s]] – y-snRNP F


===Small nuclear ribonucleoprotein binary complex===
''Small nuclear ribonucleoprotein binary complex''


[[3plu]], [[3plv]] – y-snRNP HINDI domain + ubiquitin-like modifier HUB1<br />
[[3plu]], [[3plv]] – y-snRNP HINDI domain + ubiquitin-like modifier HUB1<br />
Line 163: Line 158:
[[2dk2]] - h-hnRNP R RRM – NMR<br />
[[2dk2]] - h-hnRNP R RRM – NMR<br />


===Heterogenous nuclear ribonucleoprotein binary complex===
''Heterogenous nuclear ribonucleoprotein binary complex''


[[2kfy]], [[2kg0]], [[2kg1]] - h-hnRNP F QRRM + DNA – NMR<br />
[[2kfy]], [[2kg0]], [[2kg1]] - h-hnRNP F QRRM + DNA – NMR<br />