1dqs: Difference between revisions

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[[Image:1dqs.gif|left|200px]]<br /><applet load="1dqs" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1dqs.gif|left|200px]]
caption="1dqs, resolution 1.8&Aring;" />
 
'''CRYSTAL STRUCTURE OF DEHYDROQUINATE SYNTHASE (DHQS) COMPLEXED WITH CARBAPHOSPHONATE, NAD+ AND ZN2+'''<br />
{{Structure
|PDB= 1dqs |SIZE=350|CAPTION= <scene name='initialview01'>1dqs</scene>, resolution 1.8&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene> and <scene name='pdbligand=CRB:[1R-(1ALPHA,3BETA,4ALPHA,5BETA)]-5-(PHOSPHONOMETHYL)-1,3,4-TRIHYDROXYCYCLOHEXANE-1-CARBOXYLIC ACID'>CRB</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/3-dehydroquinate_synthase 3-dehydroquinate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.4 4.2.3.4]
|GENE= PART OF AROMA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=162425 Emericella nidulans])
}}
 
'''CRYSTAL STRUCTURE OF DEHYDROQUINATE SYNTHASE (DHQS) COMPLEXED WITH CARBAPHOSPHONATE, NAD+ AND ZN2+'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1DQS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Emericella_nidulans Emericella nidulans] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=CL:'>CL</scene>, <scene name='pdbligand=NAD:'>NAD</scene> and <scene name='pdbligand=CRB:'>CRB</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/3-dehydroquinate_synthase 3-dehydroquinate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.4 4.2.3.4] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DQS OCA].  
1DQS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Emericella_nidulans Emericella nidulans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DQS OCA].  


==Reference==
==Reference==
Structure of dehydroquinate synthase reveals an active site capable of multistep catalysis., Carpenter EP, Hawkins AR, Frost JW, Brown KA, Nature. 1998 Jul 16;394(6690):299-302. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9685163 9685163]
Structure of dehydroquinate synthase reveals an active site capable of multistep catalysis., Carpenter EP, Hawkins AR, Frost JW, Brown KA, Nature. 1998 Jul 16;394(6690):299-302. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9685163 9685163]
[[Category: 3-dehydroquinate synthase]]
[[Category: 3-dehydroquinate synthase]]
[[Category: Emericella nidulans]]
[[Category: Emericella nidulans]]
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[[Category: zn2+ binding]]
[[Category: zn2+ binding]]


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