1dth: Difference between revisions

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[[Image:1dth.gif|left|200px]]<br /><applet load="1dth" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1dth.gif|left|200px]]
caption="1dth, resolution 2.0&Aring;" />
 
'''METALLOPROTEASE'''<br />
{{Structure
|PDB= 1dth |SIZE=350|CAPTION= <scene name='initialview01'>1dth</scene>, resolution 2.0&Aring;
|SITE= <scene name='pdbsite=CAA:Ca+Ion+Binding+Site'>CAA</scene>, <scene name='pdbsite=CAB:Ca+Ion+Binding+Site'>CAB</scene>, <scene name='pdbsite=ZNA:Zn+Binding+Site'>ZNA</scene> and <scene name='pdbsite=ZNB:Zn+Binding+Site'>ZNB</scene>
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=BAT:4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE'>BAT</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Atrolysin_C Atrolysin C], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.42 3.4.24.42]
|GENE=
}}
 
'''METALLOPROTEASE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1DTH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Crotalus_atrox Crotalus atrox] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=BAT:'>BAT</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Atrolysin_C Atrolysin C], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.42 3.4.24.42] Known structural/functional Sites: <scene name='pdbsite=CAA:Ca+Ion+Binding+Site'>CAA</scene>, <scene name='pdbsite=CAB:Ca+Ion+Binding+Site'>CAB</scene>, <scene name='pdbsite=ZNA:Zn+Binding+Site'>ZNA</scene> and <scene name='pdbsite=ZNB:Zn+Binding+Site'>ZNB</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTH OCA].  
1DTH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Crotalus_atrox Crotalus atrox]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTH OCA].  


==Reference==
==Reference==
Batimastat, a potent matrix mealloproteinase inhibitor, exhibits an unexpected mode of binding., Botos I, Scapozza L, Zhang D, Liotta LA, Meyer EF, Proc Natl Acad Sci U S A. 1996 Apr 2;93(7):2749-54. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8610113 8610113]
Batimastat, a potent matrix mealloproteinase inhibitor, exhibits an unexpected mode of binding., Botos I, Scapozza L, Zhang D, Liotta LA, Meyer EF, Proc Natl Acad Sci U S A. 1996 Apr 2;93(7):2749-54. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8610113 8610113]
[[Category: Atrolysin C]]
[[Category: Atrolysin C]]
[[Category: Crotalus atrox]]
[[Category: Crotalus atrox]]
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[[Category: zinc]]
[[Category: zinc]]


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