1dx4: Difference between revisions

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[[Image:1dx4.gif|left|200px]]<br /><applet load="1dx4" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1dx4.gif|left|200px]]
caption="1dx4, resolution 2.7&Aring;" />
 
'''ACHE FROM DROSOPHILA MELANOGASTER COMPLEX WITH TACRINE DERIVATIVE 9-(3-PHENYLMETHYLAMINO)-1,2,3,4-TETRAHYDROACRIDINE'''<br />
{{Structure
|PDB= 1dx4 |SIZE=350|CAPTION= <scene name='initialview01'>1dx4</scene>, resolution 2.7&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=760:9-(3-PHENYLMETHYLAMINO)-1,2,3,4-TETRAHYDROACRIDINE'>760</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7]
|GENE=
}}
 
'''ACHE FROM DROSOPHILA MELANOGASTER COMPLEX WITH TACRINE DERIVATIVE 9-(3-PHENYLMETHYLAMINO)-1,2,3,4-TETRAHYDROACRIDINE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1DX4 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster] with <scene name='pdbligand=NAG:'>NAG</scene>, <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=760:'>760</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DX4 OCA].  
1DX4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DX4 OCA].  


==Reference==
==Reference==
Three-dimensional structures of Drosophila melanogaster acetylcholinesterase and of its complexes with two potent inhibitors., Harel M, Kryger G, Rosenberry TL, Mallender WD, Lewis T, Fletcher RJ, Guss JM, Silman I, Sussman JL, Protein Sci. 2000 Jun;9(6):1063-72. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10892800 10892800]
Three-dimensional structures of Drosophila melanogaster acetylcholinesterase and of its complexes with two potent inhibitors., Harel M, Kryger G, Rosenberry TL, Mallender WD, Lewis T, Fletcher RJ, Guss JM, Silman I, Sussman JL, Protein Sci. 2000 Jun;9(6):1063-72. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10892800 10892800]
[[Category: Acetylcholinesterase]]
[[Category: Acetylcholinesterase]]
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
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[[Category: synapse]]
[[Category: synapse]]


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