Plasmepsin: Difference between revisions
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{{STRUCTURE_3fns| right| PDB=3fns | SCENE= |CAPTION=Plasmepsin dimer witn Zn+2 ions (grey), [[3fns]] }} | {{STRUCTURE_3fns| right| PDB=3fns | SCENE= |CAPTION=Plasmepsin dimer witn Zn+2 ions (grey), [[3fns]] }} | ||
[[Plasmepsin]] (Plm) is a hemoglobin-degrading enzyme produced by the plasmodium parasite. It is a potential target for anti-malaria drugs. It is an aspartic acid protease having 2 aspartic acid residues in the active site. Ten Plm isoforms are known which are named Plm I, II, etc and '''Histo-Aspartic Protease (HAP)'''. '''ProPml II''' exhibits a large shift between its domains which renders the protease inactive. | [[Plasmepsin]] (Plm) is a hemoglobin-degrading enzyme produced by the plasmodium parasite. It is a potential target for anti-malaria drugs. It is an aspartic acid protease having 2 aspartic acid residues in the active site. Ten Plm isoforms are known which are named Plm I, II, etc and '''Histo-Aspartic Protease (HAP)'''. '''ProPml II''' exhibits a large shift between its domains which renders the protease inactive. | ||
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