4pk6: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Crystal structure of the indoleamine 2,3-dioxygenagse 1 (IDO1) complexed with imidazothiazole derivative==

~~The entry~~ 4pk6 is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4pk6]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PK6 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PK6 FirstGlance].

~~Authors~~: ~~Kohno~~, T., ~~Tojo~~, S., Ishii, T., Kamioka, S.

</td></tr><tr><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=PKL:N-[2-(3-CHLOROPHENYL)ETHYL]-3-(4-METHYLPHENYL)IMIDAZO[2,1-B][1,3]THIAZOLE-5-CARBOXAMIDE'>PKL</scene>

<tr><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[4pk5|4pk5]]</td></tr>

~~Description~~: ~~Crystal structure of the indoleamine 2~~,3-dioxygenagse 1 ~~(IDO1) complexed with imidazothiazole derivative~~

<tr><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Indoleamine_2,3-dioxygenase Indoleamine 2,3-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.52 1.13.11.52] </td></tr>

<tr><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pk6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pk6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pk6 RCSB], [http://www.ebi.ac.uk/pdbsum/4pk6 PDBsum]</td></tr>

<table>

__TOC__

</StructureSection>

[[Category: Indoleamine 2,3-dioxygenase]]

[[Category: Ishii, T.]]

[[Category: Kamioka, S.]]

[[Category: Kohno, T.]]

[[Category: Tojo, S.]]

[[Category: 3-dioxygenagse 1]]

[[Category: Imidazothiazole]]

[[Category: Indoleamine 2]]

[[Category: Induced fit]]

[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]

[[Category: Structure based drug discovery]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Crystal structure of the indoleamine 2,3-dioxygenagse 1 (IDO1) complexed with imidazothiazole derivative==
+<StructureSection load='4pk6' size='340' side='right' caption='[[4pk6]], [[Resolution|resolution]] 3.45&Aring;' scene=''>
-The entry 4pk6 is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4pk6]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PK6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PK6 FirstGlance]. <br>
-Authors: Kohno, T., Tojo, S., Ishii, T., Kamioka, S.
+</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=PKL:N-[2-(3-CHLOROPHENYL)ETHYL]-3-(4-METHYLPHENYL)IMIDAZO[2,1-B][1,3]THIAZOLE-5-CARBOXAMIDE'>PKL</scene><br>
+<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4pk5|4pk5]]</td></tr>
-Description: Crystal structure of the indoleamine 2,3-dioxygenagse 1 (IDO1) complexed with imidazothiazole derivative
+<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Indoleamine_2,3-dioxygenase Indoleamine 2,3-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.52 1.13.11.52] </span></td></tr>
+<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pk6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pk6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pk6 RCSB], [http://www.ebi.ac.uk/pdbsum/4pk6 PDBsum]</span></td></tr>
+<table>
+__TOC__
+</StructureSection>
+[[Category: Indoleamine 2,3-dioxygenase]]
+[[Category: Ishii, T.]]
+[[Category: Kamioka, S.]]
+[[Category: Kohno, T.]]
+[[Category: Tojo, S.]]
+[[Category: 3-dioxygenagse 1]]
+[[Category: Imidazothiazole]]
+[[Category: Indoleamine 2]]
+[[Category: Induced fit]]
+[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
+[[Category: Structure based drug discovery]]