4pl4: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Crystal structure of murine IRE1 in complex with OICR464 inhibitor==

~~The entry~~ 4pl4 is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4pl4]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PL4 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PL4 FirstGlance].

~~Authors~~: ~~Sanches~~, M., ~~Duffy~~, N., ~~Talukdar~~, M., ~~Thevakumaran~~, N., ~~Chiovitti~~, D., Al-awar, R., Patterson, J.B., Sicheri, F.

</td></tr><tr><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=31K:2-METHOXY-6-METHYL-4-(4-METHYL-3,4-DIHYDRO-2H-1,4-BENZOXAZIN-7-YL)PHENOL'>31K</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEU:2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL'>PEU</scene>

<tr><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[4pl3|4pl3]], [[4pl5|4pl5]]</td></tr>

~~Description~~:

<tr><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pl4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pl4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pl4 RCSB], [http://www.ebi.ac.uk/pdbsum/4pl4 PDBsum]</td></tr>

<table>

__TOC__

</StructureSection>

[[Category: Al-awar, R.]]

[[Category: Chiovitti, D.]]

[[Category: Duffy, N.]]

[[Category: Patterson, J B.]]

[[Category: Sanches, M.]]

[[Category: Sicheri, F.]]

[[Category: Talukdar, M.]]

[[Category: Thevakumaran, N.]]

[[Category: Endoribonuclease]]

[[Category: Inhibitor complex]]

[[Category: Schiff base]]

[[Category: Unfolded protein response]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Crystal structure of murine IRE1 in complex with OICR464 inhibitor==
+<StructureSection load='4pl4' size='340' side='right' caption='[[4pl4]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
-The entry 4pl4 is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4pl4]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PL4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PL4 FirstGlance]. <br>
-Authors: Sanches, M., Duffy, N., Talukdar, M., Thevakumaran, N., Chiovitti, D., Al-awar, R., Patterson, J.B., Sicheri, F.
+</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=31K:2-METHOXY-6-METHYL-4-(4-METHYL-3,4-DIHYDRO-2H-1,4-BENZOXAZIN-7-YL)PHENOL'>31K</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEU:2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL'>PEU</scene><br>
+<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4pl3|4pl3]], [[4pl5|4pl5]]</td></tr>
-Description:
+<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pl4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pl4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pl4 RCSB], [http://www.ebi.ac.uk/pdbsum/4pl4 PDBsum]</span></td></tr>
+<table>
+__TOC__
+</StructureSection>
+[[Category: Al-awar, R.]]
+[[Category: Chiovitti, D.]]
+[[Category: Duffy, N.]]
+[[Category: Patterson, J B.]]
+[[Category: Sanches, M.]]
+[[Category: Sicheri, F.]]
+[[Category: Talukdar, M.]]
+[[Category: Thevakumaran, N.]]
+[[Category: Endoribonuclease]]
+[[Category: Inhibitor complex]]
+[[Category: Schiff base]]
+[[Category: Unfolded protein response]]