1e7r: Difference between revisions

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[[Image:1e7r.jpg|left|200px]]<br /><applet load="1e7r" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1e7r.jpg|left|200px]]
caption="1e7r, resolution 1.6&Aring;" />
 
'''GDP 4-KETO-6-DEOXY-D-MANNOSE EPIMERASE REDUCTASE Y136E'''<br />
{{Structure
|PDB= 1e7r |SIZE=350|CAPTION= <scene name='initialview01'>1e7r</scene>, resolution 1.6&Aring;
|SITE= <scene name='pdbsite=AC1:Nap+Binding+Site+For+Chain+A'>AC1</scene>, <scene name='pdbsite=AC2:Uvw+Binding+Site+For+Chain+A'>AC2</scene> and <scene name='pdbsite=CAT:Catalytic+Triad+Residue+GLU+A136+Is+Mutated+The+Native+B+...'>CAT</scene>
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=UVW:ACETYLPHOSPHATE'>UVW</scene> and <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>
|ACTIVITY=
|GENE=
}}
 
'''GDP 4-KETO-6-DEOXY-D-MANNOSE EPIMERASE REDUCTASE Y136E'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1E7R is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=NAP:'>NAP</scene>, <scene name='pdbligand=UVW:'>UVW</scene> and <scene name='pdbligand=TRS:'>TRS</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Sites: <scene name='pdbsite=AC1:Nap+Binding+Site+For+Chain+A'>AC1</scene>, <scene name='pdbsite=AC2:Uvw+Binding+Site+For+Chain+A'>AC2</scene> and <scene name='pdbsite=CAT:Catalytic+Triad+Residue+GLU+A136+Is+Mutated+The+Native+B+...'>CAT</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E7R OCA].  
1E7R is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E7R OCA].  


==Reference==
==Reference==
Probing the catalytic mechanism of GDP-4-keto-6-deoxy-d-mannose Epimerase/Reductase by kinetic and crystallographic characterization of site-specific mutants., Rosano C, Bisso A, Izzo G, Tonetti M, Sturla L, De Flora A, Bolognesi M, J Mol Biol. 2000 Oct 13;303(1):77-91. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11021971 11021971]
Probing the catalytic mechanism of GDP-4-keto-6-deoxy-d-mannose Epimerase/Reductase by kinetic and crystallographic characterization of site-specific mutants., Rosano C, Bisso A, Izzo G, Tonetti M, Sturla L, De Flora A, Bolognesi M, J Mol Biol. 2000 Oct 13;303(1):77-91. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11021971 11021971]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: sdr]]
[[Category: sdr]]


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