Purine repressor: Difference between revisions
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<StructureSection load='1qp4' size='350' side='right' caption='Structure of purine processor complex with DNA and hypoxanthine (PDB entry [[1qp4]])' scene=''> | <StructureSection load='1qp4' size='350' side='right' caption='Structure of purine processor complex with DNA (green) and hypoxanthine (PDB entry [[1qp4]])' scene=''> | ||
'''Purine repressor''' (PurR) is a member of the lac repressor family. PurP binds DNA via a highly conserved helix-turn-helix at the N terminal (DBD). PurP contains a co-repressor binding domain as well (CBD). PurP binds to a 16-bp operator sequence and co-regulates genes which are involved in the biosynthesis of purine and pyrimidine nucleotides. | '''Purine repressor''' (PurR) is a member of the lac repressor family. PurP binds DNA via a highly conserved helix-turn-helix at the N terminal (DBD). PurP contains a co-repressor binding domain as well (CBD). PurP binds to a 16-bp operator sequence and co-regulates genes which are involved in the biosynthesis of purine and pyrimidine nucleotides. | ||
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[[1jhz]] - EcPurR CBD (mutant) + Mg <br /> | [[1jhz]] - EcPurR CBD (mutant) + Mg <br /> | ||
===PurP complex with DNA and nucleotide=== | |||
[[1pnr]], [[1bdi]], [[1qp0]], [[1qp4]], [[1qpz]], [[1qqb]] - EcPurR + DNA + hypoxanthine <br /> | [[1pnr]], [[1bdi]], [[1qp0]], [[1qp4]], [[1qpz]], [[1qqb]] - EcPurR + DNA + hypoxanthine <br /> | ||
