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{{STRUCTURE_4g1p|  PDB=4g1p  |  SCENE=  }}
==Structural and Mechanistic Basis of Substrate Recognition by Novel Di-peptidase Dug1p From Saccharomyces cerevisiae==
===Structural and Mechanistic Basis of Substrate Recognition by Novel Di-peptidase Dug1p From Saccharomyces cerevisiae===
<StructureSection load='4g1p' size='340' side='right' caption='[[4g1p]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
 
== Structural highlights ==
==Function==
<table><tr><td colspan='2'>[[4g1p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G1P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4G1P FirstGlance]. <br>
[[http://www.uniprot.org/uniprot/DUG1_YEAST DUG1_YEAST]] Catalytic component of the GSH degradosomal complex involved in the degradation of glutathione (GSH) and other peptides containing a gamma-glu-X bond. Functions also in a DUG2-DUG3-independent manner as a dipeptidase with high specificity for Cys-Gly and no activity toward tri- or tetrapeptides.<ref>PMID:17179087</ref> <ref>PMID:19346245</ref>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CYS:CYSTEINE'>CYS</scene>, <scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
 
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Dug1p ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
==About this Structure==
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4g1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g1p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4g1p RCSB], [http://www.ebi.ac.uk/pdbsum/4g1p PDBsum]</span></td></tr>
[[4g1p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G1P OCA].  
<table>
 
__TOC__
==Reference==
</StructureSection>
<references group="xtra"/><references/>
[[Category: Baker's yeast]]
[[Category: Saccharomyces cerevisiae s288c]]
[[Category: Kumaran, S.]]
[[Category: Kumaran, S.]]
[[Category: Mittal, M.]]
[[Category: Mittal, M.]]

Revision as of 05:37, 24 September 2014

Structural and Mechanistic Basis of Substrate Recognition by Novel Di-peptidase Dug1p From Saccharomyces cerevisiae

4g1p, resolution 2.55Å

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