1ek6: Difference between revisions

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[[Image:1ek6.gif|left|200px]]<br /><applet load="1ek6" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1ek6.gif|left|200px]]
caption="1ek6, resolution 1.50&Aring;" />
 
'''STRUCTURE OF HUMAN UDP-GALACTOSE 4-EPIMERASE COMPLEXED WITH NADH AND UDP-GLUCOSE'''<br />
{{Structure
|PDB= 1ek6 |SIZE=350|CAPTION= <scene name='initialview01'>1ek6</scene>, resolution 1.50&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene>, <scene name='pdbligand=UPG:URIDINE-5'-DIPHOSPHATE-GLUCOSE'>UPG</scene> and <scene name='pdbligand=TMA:TETRAMETHYLAMMONIUM ION'>TMA</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/UDP-glucose_4-epimerase UDP-glucose 4-epimerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.3.2 5.1.3.2]
|GENE=
}}
 
'''STRUCTURE OF HUMAN UDP-GALACTOSE 4-EPIMERASE COMPLEXED WITH NADH AND UDP-GLUCOSE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1EK6 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=NAI:'>NAI</scene>, <scene name='pdbligand=UPG:'>UPG</scene> and <scene name='pdbligand=TMA:'>TMA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/UDP-glucose_4-epimerase UDP-glucose 4-epimerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.3.2 5.1.3.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EK6 OCA].  
1EK6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EK6 OCA].  


==Reference==
==Reference==
Crystallographic evidence for Tyr 157 functioning as the active site base in human UDP-galactose 4-epimerase., Thoden JB, Wohlers TM, Fridovich-Keil JL, Holden HM, Biochemistry. 2000 May 16;39(19):5691-701. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10801319 10801319]
Crystallographic evidence for Tyr 157 functioning as the active site base in human UDP-galactose 4-epimerase., Thoden JB, Wohlers TM, Fridovich-Keil JL, Holden HM, Biochemistry. 2000 May 16;39(19):5691-701. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10801319 10801319]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: short-chain dehydrogenase]]
[[Category: short-chain dehydrogenase]]


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