1eko: Difference between revisions

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[[Image:1eko.jpg|left|200px]]<br /><applet load="1eko" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1eko.jpg|left|200px]]
caption="1eko, resolution 2.2&Aring;" />
 
'''PIG ALDOSE REDUCTASE COMPLEXED WITH IDD384 INHIBITOR'''<br />
{{Structure
|PDB= 1eko |SIZE=350|CAPTION= <scene name='initialview01'>1eko</scene>, resolution 2.2&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene> and <scene name='pdbligand=I84:[2,6-DIMETHYL-4-(2-O-TOLYL-ACETYLAMINO)-BENZENESULFONYL]-GLYCINE'>I84</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21]
|GENE=
}}
 
'''PIG ALDOSE REDUCTASE COMPLEXED WITH IDD384 INHIBITOR'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1EKO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa] with <scene name='pdbligand=NAP:'>NAP</scene> and <scene name='pdbligand=I84:'>I84</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EKO OCA].  
1EKO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EKO OCA].  


==Reference==
==Reference==
The structure of human aldose reductase bound to the inhibitor IDD384., Calderone V, Chevrier B, Van Zandt M, Lamour V, Howard E, Poterszman A, Barth P, Mitschler A, Lu J, Dvornik DM, Klebe G, Kraemer O, Moorman AR, Moras D, Podjarny A, Acta Crystallogr D Biol Crystallogr. 2000 May;56(Pt 5):536-40. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10771421 10771421]
The structure of human aldose reductase bound to the inhibitor IDD384., Calderone V, Chevrier B, Van Zandt M, Lamour V, Howard E, Poterszman A, Barth P, Mitschler A, Lu J, Dvornik DM, Klebe G, Kraemer O, Moorman AR, Moras D, Podjarny A, Acta Crystallogr D Biol Crystallogr. 2000 May;56(Pt 5):536-40. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10771421 10771421]
[[Category: Aldehyde reductase]]
[[Category: Aldehyde reductase]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: inhibition]]
[[Category: inhibition]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:28:44 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:56:54 2008''
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