1exa: Difference between revisions

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[[Image:1exa.gif|left|200px]]~~<br /><applet load~~="1exa~~" size~~="350~~" color~~=~~"white" frame~~=~~"true" align="right" spinBox="true"~~

[[Image:1exa.gif|left|200px]]

~~caption="~~1exa, resolution 1.59Å" />

'''ENANTIOMER DISCRIMINATION ILLUSTRATED BY CRYSTAL STRUCTURES OF THE HUMAN RETINOIC ACID RECEPTOR HRARGAMMA LIGAND BINDING DOMAIN: THE COMPLEX WITH THE ACTIVE R-ENANTIOMER BMS270394.'''~~<br />~~

{{Structure

|PDB= 1exa |SIZE=350|CAPTION= <scene name='initialview01'>1exa</scene>, resolution 1.59Å

|SITE=

|LIGAND= <scene name='pdbligand=394:R-3-FLUORO-4-[2-HYDROXY-2-(5,5,8,8-TETRAMETHYL-5,6,7,8,-TETRAHYDRO-NAPHTALEN-2-YL)-ACETYLAMINO]-BENZOIC+ACID'>394</scene> and <scene name='pdbligand=LMU:DODECYL-ALPHA-D-MALTOSIDE'>LMU</scene>

|ACTIVITY=

|GENE=

}}

'''ENANTIOMER DISCRIMINATION ILLUSTRATED BY CRYSTAL STRUCTURES OF THE HUMAN RETINOIC ACID RECEPTOR HRARGAMMA LIGAND BINDING DOMAIN: THE COMPLEX WITH THE ACTIVE R-ENANTIOMER BMS270394.'''

==Overview==

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==About this Structure==

1EXA is a [~~http://en.wikipedia.org/wiki/Single_protein~~ Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens~~] with <scene name='pdbligand=394:'>394</scene> and <scene name='pdbligand=LMU:'>LMU</scene> as [http://en.wikipedia.org/wiki/ligands ligands~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EXA OCA].

1EXA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EXA OCA].

==Reference==

Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARgamma., Klaholz BP, Mitschler A, Belema M, Zusi C, Moras D, Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6322-7. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~10841540 10841540]

Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARgamma., Klaholz BP, Mitschler A, Belema M, Zusi C, Moras D, Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6322-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10841540 10841540]

[[Category: Homo sapiens]]

[[Category: Single protein]]

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[[Category: antiparallel alpha-helical sandwich fold]]

[[Category: enantiomer discrimination]]

[[Category: retinoid ligand ~~complexes~~]]

[[Category: retinoid ligand complex]]

[[Category: spine]]

[[Category: structural ~~genomics~~]]

[[Category: structural genomic]]

[[Category: structural proteomics in europe]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu ~~Feb 21 12~~:32:33 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:01:28 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1exa.gif|left|200px]]<br /><applet load="1exa" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1exa.gif|left|200px]]
-caption="1exa, resolution 1.59&Aring;" />
-'''ENANTIOMER DISCRIMINATION ILLUSTRATED BY CRYSTAL STRUCTURES OF THE HUMAN RETINOIC ACID RECEPTOR HRARGAMMA LIGAND BINDING DOMAIN: THE COMPLEX WITH THE ACTIVE R-ENANTIOMER BMS270394.'''<br />
+ {{Structure
+|PDB= 1exa |SIZE=350|CAPTION= <scene name='initialview01'>1exa</scene>, resolution 1.59&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=394:R-3-FLUORO-4-[2-HYDROXY-2-(5,5,8,8-TETRAMETHYL-5,6,7,8,-TETRAHYDRO-NAPHTALEN-2-YL)-ACETYLAMINO]-BENZOIC+ACID'>394</scene> and <scene name='pdbligand=LMU:DODECYL-ALPHA-D-MALTOSIDE'>LMU</scene>
+|ACTIVITY=
+|GENE=
+}}
+'''ENANTIOMER DISCRIMINATION ILLUSTRATED BY CRYSTAL STRUCTURES OF THE HUMAN RETINOIC ACID RECEPTOR HRARGAMMA LIGAND BINDING DOMAIN: THE COMPLEX WITH THE ACTIVE R-ENANTIOMER BMS270394.'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-EXA is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=394:'>394</scene> and <scene name='pdbligand=LMU:'>LMU</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EXA OCA].
+EXA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EXA OCA].
 ==Reference==
-Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARgamma., Klaholz BP, Mitschler A, Belema M, Zusi C, Moras D, Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6322-7. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10841540 10841540]
+Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARgamma., Klaholz BP, Mitschler A, Belema M, Zusi C, Moras D, Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6322-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10841540 10841540]
 [[Category: Homo sapiens]]
 [[Category: Single protein]]
@@ Line 23: / Line 32: @@
 [[Category: antiparallel alpha-helical sandwich fold]]
 [[Category: enantiomer discrimination]]
-[[Category: retinoid ligand complexes]]
+[[Category: retinoid ligand complex]]
 [[Category: spine]]
-[[Category: structural genomics]]
+[[Category: structural genomic]]
 [[Category: structural proteomics in europe]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:32:33 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:01:28 2008''