1eye: Difference between revisions

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[[Image:1eye.gif|left|200px]]<br /><applet load="1eye" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1eye.gif|left|200px]]
caption="1eye, resolution 1.7&Aring;" />
 
'''1.7 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF 6-HYDROXYMETHYL-7,8-DIHYDROPTEROATE SYNTHASE (DHPS) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH 6-HYDROXYMETHYLPTERIN MONOPHOSPHATE'''<br />
{{Structure
|PDB= 1eye |SIZE=350|CAPTION= <scene name='initialview01'>1eye</scene>, resolution 1.7&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=PMM:PTERIN-6-YL-METHYL-MONOPHOSPHATE'>PMM</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Dihydropteroate_synthase Dihydropteroate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.15 2.5.1.15]
|GENE=
}}
 
'''1.7 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF 6-HYDROXYMETHYL-7,8-DIHYDROPTEROATE SYNTHASE (DHPS) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH 6-HYDROXYMETHYLPTERIN MONOPHOSPHATE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1EYE is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis] with <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=PMM:'>PMM</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Dihydropteroate_synthase Dihydropteroate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.15 2.5.1.15] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EYE OCA].  
1EYE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EYE OCA].  


==Reference==
==Reference==
Crystal structure of Mycobacterium tuberculosis 7,8-dihydropteroate synthase in complex with pterin monophosphate: new insight into the enzymatic mechanism and sulfa-drug action., Baca AM, Sirawaraporn R, Turley S, Sirawaraporn W, Hol WG, J Mol Biol. 2000 Oct 6;302(5):1193-212. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11007651 11007651]
Crystal structure of Mycobacterium tuberculosis 7,8-dihydropteroate synthase in complex with pterin monophosphate: new insight into the enzymatic mechanism and sulfa-drug action., Baca AM, Sirawaraporn R, Turley S, Sirawaraporn W, Hol WG, J Mol Biol. 2000 Oct 6;302(5):1193-212. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11007651 11007651]
[[Category: Dihydropteroate synthase]]
[[Category: Dihydropteroate synthase]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: alpha-beta barrel]]
[[Category: alpha-beta barrel]]


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