1f4d: Difference between revisions

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[[Image:1f4d.jpg|left|200px]]<br /><applet load="1f4d" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1f4d.jpg|left|200px]]
caption="1f4d, resolution 2.15&Aring;" />
 
'''CRYSTAL STRUCTURE OF E. COLI THYMIDYLATE SYNTHASE C146S, L143C COVALENTLY MODIFIED AT C143 WITH N-[TOSYL-D-PROLINYL]AMINO-ETHANETHIOL'''<br />
{{Structure
|PDB= 1f4d |SIZE=350|CAPTION= <scene name='initialview01'>1f4d</scene>, resolution 2.15&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TP2:N-[TOSYL-D-PROLINYL]AMINO-ETHANETHIOL'>TP2</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45]
|GENE=
}}
 
'''CRYSTAL STRUCTURE OF E. COLI THYMIDYLATE SYNTHASE C146S, L143C COVALENTLY MODIFIED AT C143 WITH N-[TOSYL-D-PROLINYL]AMINO-ETHANETHIOL'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1F4D is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=TP2:'>TP2</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F4D OCA].  
1F4D is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F4D OCA].  


==Reference==
==Reference==
Site-directed ligand discovery., Erlanson DA, Braisted AC, Raphael DR, Randal M, Stroud RM, Gordon EM, Wells JA, Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9367-72. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10944209 10944209]
Site-directed ligand discovery., Erlanson DA, Braisted AC, Raphael DR, Randal M, Stroud RM, Gordon EM, Wells JA, Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9367-72. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10944209 10944209]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: SO4]]
[[Category: SO4]]
[[Category: TP2]]
[[Category: TP2]]
[[Category: crystal structure of e. coli thymidylate synthase c146s]]
[[Category: crystal structure of e. coli thymidylate synthase c146]]
[[Category: l143c covalently modified at c143 with n-[tosyl-d-prolinyl]amino-ethanethiol]]
[[Category: l143c covalently modified at c143 with n-[tosyl-d-prolinyl]amino-ethanethiol]]


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