1fdt: Difference between revisions

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[[Image:1fdt.gif|left|200px]]<br /><applet load="1fdt" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1fdt.gif|left|200px]]
caption="1fdt, resolution 2.2&Aring;" />
 
'''HUMAN 17-BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE 1 COMPLEXED WITH ESTRADIOL AND NADP+'''<br />
{{Structure
|PDB= 1fdt |SIZE=350|CAPTION= <scene name='initialview01'>1fdt</scene>, resolution 2.2&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=EST:ESTRADIOL'>EST</scene> and <scene name='pdbligand=NAP:NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE'>NAP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Estradiol_17-beta-dehydrogenase Estradiol 17-beta-dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.62 1.1.1.62]
|GENE=
}}
 
'''HUMAN 17-BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE 1 COMPLEXED WITH ESTRADIOL AND NADP+'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1FDT is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=EST:'>EST</scene> and <scene name='pdbligand=NAP:'>NAP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Estradiol_17-beta-dehydrogenase Estradiol 17-beta-dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.62 1.1.1.62] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FDT OCA].  
1FDT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FDT OCA].  


==Reference==
==Reference==
The structure of a complex of human 17beta-hydroxysteroid dehydrogenase with estradiol and NADP+ identifies two principal targets for the design of inhibitors., Breton R, Housset D, Mazza C, Fontecilla-Camps JC, Structure. 1996 Aug 15;4(8):905-15. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8805577 8805577]
The structure of a complex of human 17beta-hydroxysteroid dehydrogenase with estradiol and NADP+ identifies two principal targets for the design of inhibitors., Breton R, Housset D, Mazza C, Fontecilla-Camps JC, Structure. 1996 Aug 15;4(8):905-15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8805577 8805577]
[[Category: Estradiol 17-beta-dehydrogenase]]
[[Category: Estradiol 17-beta-dehydrogenase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: dehydrogenase]]
[[Category: dehydrogenase]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:37:38 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:07:50 2008''
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