1p85: Difference between revisions

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[[Image:1p85.png|left|200px]]
==Real space refined coordinates of the 50S subunit fitted into the low resolution cryo-EM map of the EF-G.GTP state of E. coli 70S ribosome==
<StructureSection load='1p85' size='340' side='right' caption='[[1p85]], [[Resolution|resolution]] 12.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1p85]] is a 26 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P85 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1P85 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gix|1gix]], [[1giy|1giy]], [[1jj2|1jj2]], [[1ibl|1ibl]], [[1lnr|1lnr]], [[1m5g|1m5g]], [[1p6g|1p6g]]</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1p85 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p85 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1p85 RCSB], [http://www.ebi.ac.uk/pdbsum/1p85 PDBsum]</span></td></tr>
<table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p8/1p85_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Cryo-EM density maps showing the 70S ribosome of E. coli in two different functional states related by a ratchet-like motion were analyzed using real-space refinement. Comparison of the two resulting atomic models shows that the ribosome changes from a compact structure to a looser one, coupled with the rearrangement of many of the proteins. Furthermore, in contrast to the unchanged inter-subunit bridges formed wholly by RNA, the bridges involving proteins undergo large conformational changes following the ratchet-like motion, suggesting an important role of ribosomal proteins in facilitating the dynamics of translation.


{{STRUCTURE_1p85|  PDB=1p85  |  SCENE=  }}
Study of the structural dynamics of the E coli 70S ribosome using real-space refinement.,Gao H, Sengupta J, Valle M, Korostelev A, Eswar N, Stagg SM, Van Roey P, Agrawal RK, Harvey SC, Sali A, Chapman MS, Frank J Cell. 2003 Jun 13;113(6):789-801. PMID:12809609<ref>PMID:12809609</ref>


===Real space refined coordinates of the 50S subunit fitted into the low resolution cryo-EM map of the EF-G.GTP state of E. coli 70S ribosome===
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 
</div>
{{ABSTRACT_PUBMED_12809609}}
 
==About this Structure==
[[1p85]] is a 26 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P85 OCA].


==See Also==
==See Also==
*[[Ribosomal protein L11|Ribosomal protein L11]]
*[[Ribosome 3D structures|Ribosome 3D structures]]
*[[Ribosomal protein L13|Ribosomal protein L13]]
== References ==
*[[Ribosomal protein L14|Ribosomal protein L14]]
<references/>
*[[Ribosomal protein L15|Ribosomal protein L15]]
__TOC__
*[[Ribosomal protein L16|Ribosomal protein L16]]
</StructureSection>
*[[Ribosomal protein L17|Ribosomal protein L17]]
*[[Ribosomal protein L18|Ribosomal protein L18]]
*[[Ribosomal protein L19|Ribosomal protein L19]]
*[[Ribosomal protein L2|Ribosomal protein L2]]
*[[Ribosomal protein L20|Ribosomal protein L20]]
*[[Ribosomal protein L22|Ribosomal protein L22]]
*[[Ribosomal protein L23|Ribosomal protein L23]]
*[[Ribosomal protein L24|Ribosomal protein L24]]
*[[Ribosomal protein L25|Ribosomal protein L25]]
*[[Ribosomal protein L27|Ribosomal protein L27]]
*[[Ribosomal protein L29|Ribosomal protein L29]]
*[[Ribosomal protein L3|Ribosomal protein L3]]
*[[Ribosomal protein L30|Ribosomal protein L30]]
*[[Ribosomal protein L32|Ribosomal protein L32]]
*[[Ribosomal protein L33|Ribosomal protein L33]]
*[[Ribosomal protein L36|Ribosomal protein L36]]
*[[Ribosomal protein L4|Ribosomal protein L4]]
*[[Ribosomal protein L5|Ribosomal protein L5]]
*[[Ribosomal protein L6|Ribosomal protein L6]]
*[[Ribosomal protein L9|Ribosomal protein L9]]
 
==Reference==
<ref group="xtra">PMID:012809609</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Agrawal, R K.]]
[[Category: Agrawal, R K.]]
Retrieved from "https://proteopedia.org/1p85"