1fr4: Difference between revisions

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[[Image:1fr4.gif|left|200px]]<br /><applet load="1fr4" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1fr4.gif|left|200px]]
caption="1fr4, resolution 1.6&Aring;" />
 
'''X-RAY CRYSTAL STRUCTURE OF COPPER-BOUND F93I/F95M/W97V CARBONIC ANHYDRASE (CAII) VARIANT'''<br />
{{Structure
|PDB= 1fr4 |SIZE=350|CAPTION= <scene name='initialview01'>1fr4</scene>, resolution 1.6&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene> and <scene name='pdbligand=SO4:SULFATE ION'>SO4</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1]
|GENE=
}}
 
'''X-RAY CRYSTAL STRUCTURE OF COPPER-BOUND F93I/F95M/W97V CARBONIC ANHYDRASE (CAII) VARIANT'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1FR4 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CU:'>CU</scene> and <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FR4 OCA].  
1FR4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FR4 OCA].  


==Reference==
==Reference==
Structural influence of hydrophobic core residues on metal binding and specificity in carbonic anhydrase II., Cox JD, Hunt JA, Compher KM, Fierke CA, Christianson DW, Biochemistry. 2000 Nov 14;39(45):13687-94. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11076507 11076507]
Structural influence of hydrophobic core residues on metal binding and specificity in carbonic anhydrase II., Cox JD, Hunt JA, Compher KM, Fierke CA, Christianson DW, Biochemistry. 2000 Nov 14;39(45):13687-94. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11076507 11076507]
[[Category: Carbonate dehydratase]]
[[Category: Carbonate dehydratase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: metal specificity]]
[[Category: metal specificity]]


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