1g6s: Difference between revisions

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[[Image:1g6s.jpg|left|200px]]<br /><applet load="1g6s" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1g6s.jpg|left|200px]]
caption="1g6s, resolution 1.50&Aring;" />
 
'''STRUCTURE OF EPSP SYNTHASE LIGANDED WITH SHIKIMATE-3-PHOSPHATE AND GLYPHOSATE'''<br />
{{Structure
|PDB= 1g6s |SIZE=350|CAPTION= <scene name='initialview01'>1g6s</scene>, resolution 1.50&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=S3P:SHIKIMATE-3-PHOSPHATE'>S3P</scene>, <scene name='pdbligand=GPJ:GLYPHOSATE'>GPJ</scene> and <scene name='pdbligand=FMT:FORMIC ACID'>FMT</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/3-phosphoshikimate_1-carboxyvinyltransferase 3-phosphoshikimate 1-carboxyvinyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.19 2.5.1.19]
|GENE= AROA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
}}
 
'''STRUCTURE OF EPSP SYNTHASE LIGANDED WITH SHIKIMATE-3-PHOSPHATE AND GLYPHOSATE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1G6S is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=S3P:'>S3P</scene>, <scene name='pdbligand=GPJ:'>GPJ</scene> and <scene name='pdbligand=FMT:'>FMT</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/3-phosphoshikimate_1-carboxyvinyltransferase 3-phosphoshikimate 1-carboxyvinyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.19 2.5.1.19] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G6S OCA].  
1G6S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G6S OCA].  


==Reference==
==Reference==
Interaction of the herbicide glyphosate with its target enzyme 5-enolpyruvylshikimate 3-phosphate synthase in atomic detail., Schonbrunn E, Eschenburg S, Shuttleworth WA, Schloss JV, Amrhein N, Evans JN, Kabsch W, Proc Natl Acad Sci U S A. 2001 Feb 13;98(4):1376-80. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11171958 11171958]
Interaction of the herbicide glyphosate with its target enzyme 5-enolpyruvylshikimate 3-phosphate synthase in atomic detail., Schonbrunn E, Eschenburg S, Shuttleworth WA, Schloss JV, Amrhein N, Evans JN, Kabsch W, Proc Natl Acad Sci U S A. 2001 Feb 13;98(4):1376-80. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11171958 11171958]
[[Category: 3-phosphoshikimate 1-carboxyvinyltransferase]]
[[Category: 3-phosphoshikimate 1-carboxyvinyltransferase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: two-domain structure; inside-out alpha-beta barrel]]
[[Category: two-domain structure; inside-out alpha-beta barrel]]


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