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[[Image:3cy1.png|left|200px]]
==Crystal structure of the cytochrome P450 CYP121 S279A mutant from M. tuberculosis==
 
<StructureSection load='3cy1' size='340' side='right' caption='[[3cy1]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
{{STRUCTURE_3cy1|  PDB=3cy1  |  SCENE=  }}
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3cy1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CY1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CY1 FirstGlance]. <br>
===Crystal structure of the cytochrome P450 CYP121 S279A mutant from M. tuberculosis===
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
 
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1n40|1n40]], [[3cxv|3cxv]], [[3cxx|3cxx]], [[3cxy|3cxy]], [[3cxz|3cxz]], [[3cy0|3cy0]]</td></tr>
 
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cyp121 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr>
==About this Structure==
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cy1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cy1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3cy1 RCSB], [http://www.ebi.ac.uk/pdbsum/3cy1 PDBsum]</span></td></tr>
[[3cy1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CY1 OCA].  
<table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cy/3cy1_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Cytochrome P450|Cytochrome P450]]
*[[Cytochrome P450|Cytochrome P450]]
__TOC__
</StructureSection>
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Leys, D.]]
[[Category: Leys, D.]]

Revision as of 07:39, 29 September 2014

Crystal structure of the cytochrome P450 CYP121 S279A mutant from M. tuberculosis

3cy1, resolution 1.75Å

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