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[[Image:3b4w.png|left|200px]]
==Crystal structure of Mycobacterium tuberculosis aldehyde dehydrogenase complexed with NAD+==
 
<StructureSection load='3b4w' size='340' side='right' caption='[[3b4w]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
{{STRUCTURE_3b4w|  PDB=3b4w  |  SCENE=  }}
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3b4w]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B4W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3B4W FirstGlance]. <br>
===Crystal structure of Mycobacterium tuberculosis aldehyde dehydrogenase complexed with NAD+===
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EOH:ETHANOL'>EOH</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
 
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rv0223c, MT0233 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 Mycobacterium tuberculosis H37Rv])</td></tr>
 
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3b4w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b4w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3b4w RCSB], [http://www.ebi.ac.uk/pdbsum/3b4w PDBsum]</span></td></tr>
==About this Structure==
<table>
[[3b4w]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B4W OCA].  
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b4/3b4w_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Aldehyde dehydrogenase|Aldehyde dehydrogenase]]
*[[Aldehyde dehydrogenase|Aldehyde dehydrogenase]]
__TOC__
</StructureSection>
[[Category: Mycobacterium tuberculosis h37rv]]
[[Category: Mycobacterium tuberculosis h37rv]]
[[Category: Hung, L-W.]]
[[Category: Hung, L-W.]]

Revision as of 07:51, 29 September 2014

Crystal structure of Mycobacterium tuberculosis aldehyde dehydrogenase complexed with NAD+

3b4w, resolution 1.80Å

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