1gfw: Difference between revisions

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[[Image:1gfw.gif|left|200px]]<br /><applet load="1gfw" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1gfw.gif|left|200px]]
caption="1gfw, resolution 2.8&Aring;" />
 
'''THE 2.8 ANGSTROM CRYSTAL STRUCTURE OF CASPASE-3 (APOPAIN OR CPP32)IN COMPLEX WITH AN ISATIN SULFONAMIDE INHIBITOR.'''<br />
{{Structure
|PDB= 1gfw |SIZE=350|CAPTION= <scene name='initialview01'>1gfw</scene>, resolution 2.8&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MSI:1-METHYL-5-(2-PHENOXYMETHYL-PYRROLIDINE-1-SULFONYL)-1H-INDOLE-2,3-DIONE'>MSI</scene>
|ACTIVITY=
|GENE=
}}
 
'''THE 2.8 ANGSTROM CRYSTAL STRUCTURE OF CASPASE-3 (APOPAIN OR CPP32)IN COMPLEX WITH AN ISATIN SULFONAMIDE INHIBITOR.'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1GFW is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MSI:'>MSI</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. This structure supersedes the now removed PDB entry 1QA8. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GFW OCA].  
1GFW is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry 1QA8. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GFW OCA].  


==Reference==
==Reference==
Potent and selective nonpeptide inhibitors of caspases 3 and 7 inhibit apoptosis and maintain cell functionality., Lee D, Long SA, Adams JL, Chan G, Vaidya KS, Francis TA, Kikly K, Winkler JD, Sung CM, Debouck C, Richardson S, Levy MA, DeWolf WE Jr, Keller PM, Tomaszek T, Head MS, Ryan MD, Haltiwanger RC, Liang PH, Janson CA, McDevitt PJ, Johanson K, Concha NO, Chan W, Abdel-Meguid SS, Badger AM, Lark MW, Nadeau DP, Suva LJ, Gowen M, Nuttall ME, J Biol Chem. 2000 May 26;275(21):16007-14. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10821855 10821855]
Potent and selective nonpeptide inhibitors of caspases 3 and 7 inhibit apoptosis and maintain cell functionality., Lee D, Long SA, Adams JL, Chan G, Vaidya KS, Francis TA, Kikly K, Winkler JD, Sung CM, Debouck C, Richardson S, Levy MA, DeWolf WE Jr, Keller PM, Tomaszek T, Head MS, Ryan MD, Haltiwanger RC, Liang PH, Janson CA, McDevitt PJ, Johanson K, Concha NO, Chan W, Abdel-Meguid SS, Badger AM, Lark MW, Nadeau DP, Suva LJ, Gowen M, Nuttall ME, J Biol Chem. 2000 May 26;275(21):16007-14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10821855 10821855]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: x-ray]]
[[Category: x-ray]]


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