3ffi: Difference between revisions

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~~[[Image:3ffi.png|left|200px]]~~

==HIV-1 RT with pyridone non-nucleoside inhibitor==

~~{{STRUCTURE_3ffi| PDB=3ffi | SCENE= }}~~

== Structural highlights ==

<table><tr><td colspan='2'>[[3ffi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hiv-1_m:b_hxb2r Hiv-1 m:b_hxb2r]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FFI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FFI FirstGlance]. <br>

===HIV-1 RT with pyridone non-nucleoside inhibitor===

</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3OB:3-CHLORO-5-({6-[2-(3,4-DIHYDROISOQUINOLIN-2(1H)-YL)-2-OXOETHYL]-3-(DIMETHYLAMINO)-2-OXO-1,2-DIHYDROPYRIDIN-4-YL}OXY)BENZONITRILE'>3OB</scene><br>

<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3e01|3e01]], [[3dya|3dya]], [[3di6|3di6]]</td></tr>

<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11706 HIV-1 M:B_HXB2R])</td></tr>

==~~About this Structure~~==

<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ffi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ffi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ffi RCSB], [http://www.ebi.ac.uk/pdbsum/3ffi PDBsum]</span></td></tr>

[[3ffi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hiv-1_m:b_hxb2r Hiv-1 m:b_hxb2r]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FFI OCA].

<table>

== Evolutionary Conservation ==

[[Image:Consurf_key_small.gif|200px|right]]

Check<jmol>

<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ff/3ffi_consurf.spt"</scriptWhenChecked>

<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>

<text>to colour the structure by Evolutionary Conservation</text>

</jmolCheckbox>

</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].

==See Also==

*[[Reverse transcriptase|Reverse transcriptase]]

__TOC__

</StructureSection>

[[Category: Hiv-1 m:b_hxb2r]]

[[Category: Harris, S F.]]

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@@ Line 1: / Line 1: @@
-[[Image:3ffi.png|left|200px]]
+==HIV-1 RT with pyridone non-nucleoside inhibitor==
+<StructureSection load='3ffi' size='340' side='right' caption='[[3ffi]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
-{{STRUCTURE_3ffi|  PDB=3ffi  |  SCENE=  }}
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3ffi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hiv-1_m:b_hxb2r Hiv-1 m:b_hxb2r]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FFI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FFI FirstGlance]. <br>
-===HIV-1 RT with pyridone non-nucleoside inhibitor===
+</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3OB:3-CHLORO-5-({6-[2-(3,4-DIHYDROISOQUINOLIN-2(1H)-YL)-2-OXOETHYL]-3-(DIMETHYLAMINO)-2-OXO-1,2-DIHYDROPYRIDIN-4-YL}OXY)BENZONITRILE'>3OB</scene><br>
+<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3e01|3e01]], [[3dya|3dya]], [[3di6|3di6]]</td></tr>
+<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11706 HIV-1 M:B_HXB2R])</td></tr>
-==About this Structure==
+<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ffi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ffi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ffi RCSB], [http://www.ebi.ac.uk/pdbsum/3ffi PDBsum]</span></td></tr>
-[[3ffi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hiv-1_m:b_hxb2r Hiv-1 m:b_hxb2r]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FFI OCA].
+<table>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ff/3ffi_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+<div style="clear:both"></div>
 ==See Also==
 *[[Reverse transcriptase|Reverse transcriptase]]
+__TOC__
+</StructureSection>
 [[Category: Hiv-1 m:b_hxb2r]]
 [[Category: Harris, S F.]]