1grh: Difference between revisions

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[[Image:1grh.gif|left|200px]]<br /><applet load="1grh" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1grh.gif|left|200px]]
caption="1grh, resolution 3.0&Aring;" />
 
'''INHIBITION OF HUMAN GLUTATHIONE REDUCTASE BY THE NITROSOUREA DRUGS 1,3-BIS(2-CHLOROETHYL)-1-NITROSOUREA AND 1-(2-CHLOROETHYL)-3-(2-HYDROXYETHYL)-1-NITROSOUREA'''<br />
{{Structure
|PDB= 1grh |SIZE=350|CAPTION= <scene name='initialview01'>1grh</scene>, resolution 3.0&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CYS:CYSTEINE'>CYS</scene> and <scene name='pdbligand=EOH:ETHANOL'>EOH</scene>
|ACTIVITY=
|GENE=
}}
 
'''INHIBITION OF HUMAN GLUTATHIONE REDUCTASE BY THE NITROSOUREA DRUGS 1,3-BIS(2-CHLOROETHYL)-1-NITROSOUREA AND 1-(2-CHLOROETHYL)-3-(2-HYDROXYETHYL)-1-NITROSOUREA'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1GRH is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ] with <scene name='pdbligand=CYS:'>CYS</scene> and <scene name='pdbligand=EOH:'>EOH</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GRH OCA].  
1GRH is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GRH OCA].  


==Reference==
==Reference==
Inhibition of human glutathione reductase by the nitrosourea drugs 1,3-bis(2-chloroethyl)-1-nitrosourea and 1-(2-chloroethyl)-3-(2-hydroxyethyl)-1-nitrosourea. A crystallographic analysis., Karplus PA, Krauth-Siegel RL, Schirmer RH, Schulz GE, Eur J Biochem. 1988 Jan 15;171(1-2):193-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=3338461 3338461]
Inhibition of human glutathione reductase by the nitrosourea drugs 1,3-bis(2-chloroethyl)-1-nitrosourea and 1-(2-chloroethyl)-3-(2-hydroxyethyl)-1-nitrosourea. A crystallographic analysis., Karplus PA, Krauth-Siegel RL, Schirmer RH, Schulz GE, Eur J Biochem. 1988 Jan 15;171(1-2):193-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/3338461 3338461]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Karplus, P A.]]
[[Category: Karplus, P A.]]
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[[Category: oxidoreductase(flavoenzyme)]]
[[Category: oxidoreductase(flavoenzyme)]]


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