1h6v: Difference between revisions

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[[Image:1h6v.gif|left|200px]]<br /><applet load="1h6v" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1h6v.gif|left|200px]]
caption="1h6v, resolution 3.0&Aring;" />
 
'''MAMMALIAN THIOREDOXIN REDUCTASE'''<br />
{{Structure
|PDB= 1h6v |SIZE=350|CAPTION= <scene name='initialview01'>1h6v</scene>, resolution 3.0&Aring;
|SITE= <scene name='pdbsite=FAA:Fad+Binding+Site+For+Chain+A'>FAA</scene>, <scene name='pdbsite=FAB:Fad+Binding+Site+For+Chain+B'>FAB</scene>, <scene name='pdbsite=FAC:Fad+Binding+Site+For+Chain+C'>FAC</scene>, <scene name='pdbsite=FAD:Fad+Binding+Site+For+Chain+D'>FAD</scene>, <scene name='pdbsite=FAE:Fad+Binding+Site+For+Chain+E'>FAE</scene>, <scene name='pdbsite=FAF:Fad+Binding+Site+For+Chain+F'>FAF</scene>, <scene name='pdbsite=NDA:Ndp+Binding+Site+For+Chain+A'>NDA</scene>, <scene name='pdbsite=NDB:Ndp+Binding+Site+For+Chain+B'>NDB</scene>, <scene name='pdbsite=NDC:Ndp+Binding+Site+For+Chain+C'>NDC</scene>, <scene name='pdbsite=NDD:Ndp+Binding+Site+For+Chain+D'>NDD</scene>, <scene name='pdbsite=NDE:Ndp+Binding+Site+For+Chain+E'>NDE</scene> and <scene name='pdbsite=NDF:Ndp+Binding+Site+For+Chain+F'>NDF</scene>
|LIGAND= <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene> and <scene name='pdbligand=NDP:NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE'>NDP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Transferred_entry:_1.8.1.9 Transferred entry: 1.8.1.9], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.4.5 1.6.4.5]
|GENE=
}}
 
'''MAMMALIAN THIOREDOXIN REDUCTASE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1H6V is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with <scene name='pdbligand=FAD:'>FAD</scene> and <scene name='pdbligand=NDP:'>NDP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Transferred_entry:_1.8.1.9 Transferred entry: 1.8.1.9], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.4.5 1.6.4.5] Known structural/functional Sites: <scene name='pdbsite=FAA:Fad+Binding+Site+For+Chain+A'>FAA</scene>, <scene name='pdbsite=FAB:Fad+Binding+Site+For+Chain+B'>FAB</scene>, <scene name='pdbsite=FAC:Fad+Binding+Site+For+Chain+C'>FAC</scene>, <scene name='pdbsite=FAD:Fad+Binding+Site+For+Chain+D'>FAD</scene>, <scene name='pdbsite=FAE:Fad+Binding+Site+For+Chain+E'>FAE</scene>, <scene name='pdbsite=FAF:Fad+Binding+Site+For+Chain+F'>FAF</scene>, <scene name='pdbsite=NDA:Ndp+Binding+Site+For+Chain+A'>NDA</scene>, <scene name='pdbsite=NDB:Ndp+Binding+Site+For+Chain+B'>NDB</scene>, <scene name='pdbsite=NDC:Ndp+Binding+Site+For+Chain+C'>NDC</scene>, <scene name='pdbsite=NDD:Ndp+Binding+Site+For+Chain+D'>NDD</scene>, <scene name='pdbsite=NDE:Ndp+Binding+Site+For+Chain+E'>NDE</scene> and <scene name='pdbsite=NDF:Ndp+Binding+Site+For+Chain+F'>NDF</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H6V OCA].  
1H6V is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H6V OCA].  


==Reference==
==Reference==
Three-dimensional structure of a mammalian thioredoxin reductase: implications for mechanism and evolution of a selenocysteine-dependent enzyme., Sandalova T, Zhong L, Lindqvist Y, Holmgren A, Schneider G, Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9533-8. Epub 2001 Jul 31. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11481439 11481439]
Three-dimensional structure of a mammalian thioredoxin reductase: implications for mechanism and evolution of a selenocysteine-dependent enzyme., Sandalova T, Zhong L, Lindqvist Y, Holmgren A, Schneider G, Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9533-8. Epub 2001 Jul 31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11481439 11481439]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: pyridine nucleotide-disulfide oxidoreductase]]
[[Category: pyridine nucleotide-disulfide oxidoreductase]]


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