1ufn: Difference between revisions

Line 1:

~~[[Image:1ufn.png|left|200px]]~~

==Solution structure of the SAND domain of the putative nuclear protein homolog (5830484A20Rik)==

~~{{STRUCTURE_1ufn| PDB=1ufn | SCENE= }}~~

== Structural highlights ==

<table><tr><td colspan='2'>[[1ufn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UFN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UFN FirstGlance]. <br>

===Solution structure of the SAND domain of the putative nuclear protein homolog (5830484A20Rik)===

</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIKEN cDNA 5830484A20 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>

<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ufn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ufn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ufn RCSB], [http://www.ebi.ac.uk/pdbsum/1ufn PDBsum], [http://www.topsan.org/Proteins/RSGI/1ufn TOPSAN]</span></td></tr>

<table>

==~~About this Structure~~==

== Disease ==

[[1ufn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UFN OCA].

[[http://www.uniprot.org/uniprot/SP110_MOUSE SP110_MOUSE]] Defects in Sp110 are a cause of severely impaired resistance to infection by M.tuberculosis.<ref>PMID:15815631</ref>

== Function ==

[[http://www.uniprot.org/uniprot/SP110_MOUSE SP110_MOUSE]] May act as a transcription factor. Plays a role in the innate immunity against intracellular pathogens. Required for resistance to M.tuberculosis and L.monocytogenes. Promotes apoptosis of infected cells.<ref>PMID:15815631</ref>

== Evolutionary Conservation ==

[[Image:Consurf_key_small.gif|200px|right]]

Check<jmol>

<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uf/1ufn_consurf.spt"</scriptWhenChecked>

<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>

<text>to colour the structure by Evolutionary Conservation</text>

</jmolCheckbox>

</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].

== References ==

__TOC__

</StructureSection>

[[Category: Mus musculus]]

[[Category: Aoki, M.]]

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@@ Line 1: / Line 1: @@
-[[Image:1ufn.png|left|200px]]
+==Solution structure of the SAND domain of the putative nuclear protein homolog (5830484A20Rik)==
+<StructureSection load='1ufn' size='340' side='right' caption='[[1ufn]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
-{{STRUCTURE_1ufn|  PDB=1ufn  |  SCENE=  }}
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1ufn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UFN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UFN FirstGlance]. <br>
-===Solution structure of the SAND domain of the putative nuclear protein homolog (5830484A20Rik)===
+</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIKEN cDNA 5830484A20 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
+<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ufn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ufn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ufn RCSB], [http://www.ebi.ac.uk/pdbsum/1ufn PDBsum], [http://www.topsan.org/Proteins/RSGI/1ufn TOPSAN]</span></td></tr>
+<table>
-==About this Structure==
+== Disease ==
-[[1ufn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UFN OCA].
+[[http://www.uniprot.org/uniprot/SP110_MOUSE SP110_MOUSE]] Defects in Sp110 are a cause of severely impaired resistance to infection by M.tuberculosis.<ref>PMID:15815631</ref>
+== Function ==
+[[http://www.uniprot.org/uniprot/SP110_MOUSE SP110_MOUSE]] May act as a transcription factor. Plays a role in the innate immunity against intracellular pathogens. Required for resistance to M.tuberculosis and L.monocytogenes. Promotes apoptosis of infected cells.<ref>PMID:15815631</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uf/1ufn_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+<div style="clear:both"></div>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Mus musculus]]
 [[Category: Aoki, M.]]