2bv8: Difference between revisions

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[[Image:2bv8.png|left|200px]]
==THE CRYSTAL STRUCTURE OF PHYCOCYANIN FROM GRACILARIA CHILENSIS.==
<StructureSection load='2bv8' size='340' side='right' caption='[[2bv8]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2bv8]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Gracilaria_chilensis Gracilaria chilensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BV8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BV8 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CYC:PHYCOCYANOBILIN'>CYC</scene>, <scene name='pdbligand=PEB:PHYCOERYTHROBILIN'>PEB</scene><br>
<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MEN:N-METHYL+ASPARAGINE'>MEN</scene></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bv8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bv8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bv8 RCSB], [http://www.ebi.ac.uk/pdbsum/2bv8 PDBsum]</span></td></tr>
<table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bv/2bv8_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Phycocyanin is a phycobiliprotein involved in light harvesting and conduction of light to the reaction centers in cyanobacteria and red algae. The structure of C-phycocyanin from Gracilaria chilensis was solved by X-ray crystallography at 2.0 A resolution in space group P2(1). An interaction model between two PC heterohexamers was built, followed by molecular dynamic refinement. The best model showed an inter-hexamer rotation of 23 degrees . The coordinates of a PC heterohexamer (alphabeta)(6) and of the PC-PC complex were used to perform energy transfer calculations between chromophores pairs using the fluorescence resonance energy transfer approach (FRET). Two main intra PC ((I)beta(3)(82)--&gt;(I)alpha(1)(84)--&gt;(I)alpha(5)(84)--&gt;(I)beta(6)(82) and (I)beta(3)(153)--&gt;(I)beta(5)(153)) and two main inter PC ((I)beta(6)(82)--&gt;(II)beta(3)(82) and (I)beta(5)(153)--&gt;(II)beta(3)(153)) pathways were proposed based on the values of the energy transfer constants calculated for all the chromophore pairs in the hexamer and in the complex.


{{STRUCTURE_2bv8|  PDB=2bv8  |  SCENE=  }}
The structure at 2 A resolution of Phycocyanin from Gracilaria chilensis and the energy transfer network in a PC-PC complex.,Contreras-Martel C, Matamala A, Bruna C, Poo-Caamano G, Almonacid D, Figueroa M, Martinez-Oyanedel J, Bunster M Biophys Chem. 2007 Feb;125(2-3):388-96. Epub 2006 Nov 10. PMID:17118524<ref>PMID:17118524</ref>


===THE CRYSTAL STRUCTURE OF PHYCOCYANIN FROM GRACILARIA CHILENSIS.===
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 
</div>
{{ABSTRACT_PUBMED_17118524}}
== References ==
 
<references/>
==About this Structure==
__TOC__
[[2bv8]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Gracilaria_chilensis Gracilaria chilensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BV8 OCA].
</StructureSection>
 
==Reference==
<ref group="xtra">PMID:017118524</ref><references group="xtra"/>
[[Category: Gracilaria chilensis]]
[[Category: Gracilaria chilensis]]
[[Category: Bruna, C.]]
[[Category: Bruna, C.]]