1i48: Difference between revisions

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[[Image:1i48.gif|left|200px]]<br /><applet load="1i48" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1i48.gif|left|200px]]
caption="1i48, resolution 3.25&Aring;" />
 
'''CYSTATHIONINE GAMMA-SYNTHASE IN COMPLEX WITH THE INHIBITOR CTCPO'''<br />
{{Structure
|PDB= 1i48 |SIZE=350|CAPTION= <scene name='initialview01'>1i48</scene>, resolution 3.25&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=PLP:PYRIDOXAL-5'-PHOSPHATE'>PLP</scene> and <scene name='pdbligand=CCO:CARBOXYMETHYLTHIO-3-(3-CHLOROPHENYL)-1,2,4-OXADIAZOL'>CCO</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Cystathionine_gamma-synthase Cystathionine gamma-synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.48 2.5.1.48]
|GENE= METB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4097 Nicotiana tabacum])
}}
 
'''CYSTATHIONINE GAMMA-SYNTHASE IN COMPLEX WITH THE INHIBITOR CTCPO'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1I48 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Nicotiana_tabacum Nicotiana tabacum] with <scene name='pdbligand=PLP:'>PLP</scene> and <scene name='pdbligand=CCO:'>CCO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Cystathionine_gamma-synthase Cystathionine gamma-synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.48 2.5.1.48] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I48 OCA].  
1I48 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Nicotiana_tabacum Nicotiana tabacum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I48 OCA].  


==Reference==
==Reference==
Crystal structures of cystathionine gamma-synthase inhibitor complexes rationalize the increased affinity of a novel inhibitor., Steegborn C, Laber B, Messerschmidt A, Huber R, Clausen T, J Mol Biol. 2001 Aug 24;311(4):789-801. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11518531 11518531]
Crystal structures of cystathionine gamma-synthase inhibitor complexes rationalize the increased affinity of a novel inhibitor., Steegborn C, Laber B, Messerschmidt A, Huber R, Clausen T, J Mol Biol. 2001 Aug 24;311(4):789-801. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11518531 11518531]
[[Category: Cystathionine gamma-synthase]]
[[Category: Cystathionine gamma-synthase]]
[[Category: Nicotiana tabacum]]
[[Category: Nicotiana tabacum]]
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[[Category: plp-dependent enzyme]]
[[Category: plp-dependent enzyme]]


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