2kaw: Difference between revisions

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~~[[Image:2kaw.png|left|200px]]~~

==NMR structure of the mDvl1 PDZ domain in complex with its inhibitor==

~~{{STRUCTURE_2kaw| PDB=2kaw | SCENE= }}~~

== Structural highlights ==

<table><tr><td colspan='2'>[[2kaw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KAW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KAW FirstGlance]. <br>

===NMR structure of the mDvl1 PDZ domain in complex with its inhibitor===

</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SUZ:[(1Z)-5-FLUORO-2-METHYL-1-{4-[METHYLSULFINYL]BENZYLIDENE}-1H-INDEN-3-YL]ACETIC+ACID'>SUZ</scene><br>

<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1mc7|1mc7]], [[1l6o|1l6o]]</td></tr>

<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Dvl1, Dvl ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>

==~~About this Structure~~==

<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kaw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kaw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kaw RCSB], [http://www.ebi.ac.uk/pdbsum/2kaw PDBsum]</span></td></tr>

[[2kaw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KAW OCA].

<table>

== Evolutionary Conservation ==

==~~Reference~~==

[[Image:Consurf_key_small.gif|200px|right]]

<~~ref group~~="~~xtra~~">~~PMID~~:~~019637179~~</~~ref~~><~~references group~~="~~xtra~~"/>

Check<jmol>

<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ka/2kaw_consurf.spt"</scriptWhenChecked>

<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>

<text>to colour the structure by Evolutionary Conservation</text>

</jmolCheckbox>

</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].

__TOC__

</StructureSection>

[[Category: Mus musculus]]

[[Category: Lee, H J.]]

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@@ Line 1: / Line 1: @@
-[[Image:2kaw.png|left|200px]]
+==NMR structure of the mDvl1 PDZ domain in complex with its inhibitor==
+<StructureSection load='2kaw' size='340' side='right' caption='[[2kaw]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
-{{STRUCTURE_2kaw|  PDB=2kaw  |  SCENE=  }}
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2kaw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KAW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KAW FirstGlance]. <br>
-===NMR structure of the mDvl1 PDZ domain in complex with its inhibitor===
+</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SUZ:[(1Z)-5-FLUORO-2-METHYL-1-{4-[METHYLSULFINYL]BENZYLIDENE}-1H-INDEN-3-YL]ACETIC+ACID'>SUZ</scene><br>
+<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1mc7|1mc7]], [[1l6o|1l6o]]</td></tr>
+<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Dvl1, Dvl ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
-==About this Structure==
+<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kaw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kaw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kaw RCSB], [http://www.ebi.ac.uk/pdbsum/2kaw PDBsum]</span></td></tr>
-[[2kaw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KAW OCA].
+<table>
+== Evolutionary Conservation ==
-==Reference==
+[[Image:Consurf_key_small.gif|200px|right]]
-<ref group="xtra">PMID:019637179</ref><references group="xtra"/>
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ka/2kaw_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+<div style="clear:both"></div>
+__TOC__
+</StructureSection>
 [[Category: Mus musculus]]
 [[Category: Lee, H J.]]