1i79: Difference between revisions

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[[Image:1i79.jpg|left|200px]]<br /><applet load="1i79" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1i79.jpg|left|200px]]
caption="1i79, resolution 2.01&Aring;" />
 
'''HUMAN S-ADENOSYLMETHIONINE DECARBOXYLASE WITH COVALENTLY BOUND PYRUVOYL GROUP AND COVALENTLY BOUND 5'-DEOXY-5'-[(3-HYDRAZINOPROPYL)METHYLAMINO]ADENOSINE'''<br />
{{Structure
|PDB= 1i79 |SIZE=350|CAPTION= <scene name='initialview01'>1i79</scene>, resolution 2.01&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MHZ:5'-DEOXY-5'-[(3-HYDRAZINOPROPYL)METHYLAMINO]ADENOSINE'>MHZ</scene> and <scene name='pdbligand=PUT:1,4-DIAMINOBUTANE'>PUT</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Adenosylmethionine_decarboxylase Adenosylmethionine decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.50 4.1.1.50]
|GENE=
}}
 
'''HUMAN S-ADENOSYLMETHIONINE DECARBOXYLASE WITH COVALENTLY BOUND PYRUVOYL GROUP AND COVALENTLY BOUND 5'-DEOXY-5'-[(3-HYDRAZINOPROPYL)METHYLAMINO]ADENOSINE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1I79 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MHZ:'>MHZ</scene> and <scene name='pdbligand=PUT:'>PUT</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Adenosylmethionine_decarboxylase Adenosylmethionine decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.50 4.1.1.50] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I79 OCA].  
1I79 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I79 OCA].  


==Reference==
==Reference==
The structural basis for substrate specificity and inhibition of human S-adenosylmethionine decarboxylase., Tolbert WD, Ekstrom JL, Mathews II, Secrist JA 3rd, Kapoor P, Pegg AE, Ealick SE, Biochemistry. 2001 Aug 14;40(32):9484-94. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11583147 11583147]
The structural basis for substrate specificity and inhibition of human S-adenosylmethionine decarboxylase., Tolbert WD, Ekstrom JL, Mathews II, Secrist JA 3rd, Kapoor P, Pegg AE, Ealick SE, Biochemistry. 2001 Aug 14;40(32):9484-94. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11583147 11583147]
[[Category: Adenosylmethionine decarboxylase]]
[[Category: Adenosylmethionine decarboxylase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: spermidine biosynthesis]]
[[Category: spermidine biosynthesis]]


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