3ckx: Difference between revisions

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[[Image:~~3ckx~~.~~png~~|~~left~~|~~200px~~]]

==Crystal structure of sterile 20-like kinase 3 (MST3, STK24) in complex with staurosporine==

== Structural highlights ==

<table><tr><td colspan='2'>[[3ckx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CKX OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CKX FirstGlance].

</td></tr><tr><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=STU:STAUROSPORINE'>STU</scene>

<tr><td class="sblockLbl">[[Non-Standard_Residue|NonStd Res:]]</td><td class="sblockDat"><scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>

<tr><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[3ckw|3ckw]]</td></tr>

<tr><td class="sblockLbl">[[Gene|Gene:]]</td><td class="sblockDat">STK24, MST3, STK3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>

<tr><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </td></tr>

<tr><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ckx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ckx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ckx RCSB], [http://www.ebi.ac.uk/pdbsum/3ckx PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/3ckx TOPSAN]</td></tr>

<table>

== Evolutionary Conservation ==

[[Image:Consurf_key_small.gif|200px|right]]

Check<jmol>

<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ck/3ckx_consurf.spt"</scriptWhenChecked>

<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>

<text>to colour the structure by Evolutionary Conservation</text>

</jmolCheckbox>

</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].

~~{{STRUCTURE_3ckx| PDB~~=~~3ckx | SCENE= }}~~

==See Also==

*[[Serine/threonine protein kinase|Serine/threonine protein kinase]]

~~===Crystal structure of sterile 20-like kinase 3 (MST3, STK24) in complex with staurosporine~~===

__TOC__

</StructureSection>

~~==About this Structure==~~

[[~~3ckx]] is a 1 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Homo_sapiens Homo sapiens~~]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin~~/~~ocashort?id=3CKX OCA].~~

[[Category: Homo sapiens]]

[[Category: Non-specific serine/threonine protein kinase]]

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-[[Image:3ckx.png|left|200px]]
+==Crystal structure of sterile 20-like kinase 3 (MST3, STK24) in complex with staurosporine==
+<StructureSection load='3ckx' size='340' side='right' caption='[[3ckx]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3ckx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CKX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CKX FirstGlance]. <br>
+</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=STU:STAUROSPORINE'>STU</scene><br>
+<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
+<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ckw|3ckw]]</td></tr>
+<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">STK24, MST3, STK3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
+<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
+<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ckx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ckx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ckx RCSB], [http://www.ebi.ac.uk/pdbsum/3ckx PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/3ckx TOPSAN]</span></td></tr>
+<table>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ck/3ckx_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+<div style="clear:both"></div>
-{{STRUCTURE_3ckx|  PDB=3ckx  |  SCENE=  }}
+==See Also==
+*[[Serine/threonine protein kinase|Serine/threonine protein kinase]]
-===Crystal structure of sterile 20-like kinase 3 (MST3, STK24) in complex with staurosporine===
+__TOC__
+</StructureSection>
-==About this Structure==
-[[3ckx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CKX OCA].
 [[Category: Homo sapiens]]
 [[Category: Non-specific serine/threonine protein kinase]]