1j17: Difference between revisions

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[[Image:1j17.gif|left|200px]]<br /><applet load="1j17" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1j17.gif|left|200px]]
caption="1j17, resolution 2.0&Aring;" />
 
'''FACTOR XA SPECIFIC INHIBITOR IN COMPLEX WITH RAT TRYPSIN MUTANT X99/175/190RT'''<br />
{{Structure
|PDB= 1j17 |SIZE=350|CAPTION= <scene name='initialview01'>1j17</scene>, resolution 2.0&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=ZEN:[4-(6-CHLORO-NAPHTHALENE-2-SULFONYL)-PIPERAZIN-1-YL]- (3,4,5,6-TETRAHYDRO-2H-[1,4']BIPYRIDINYL-4-YL)- METHANONE'>ZEN</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4]
|GENE=
}}
 
'''FACTOR XA SPECIFIC INHIBITOR IN COMPLEX WITH RAT TRYPSIN MUTANT X99/175/190RT'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1J17 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with <scene name='pdbligand=CA:'>CA</scene>, <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=ZEN:'>ZEN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J17 OCA].  
1J17 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J17 OCA].  


==Reference==
==Reference==
Reconstructing the binding site of factor Xa in trypsin reveals ligand-induced structural plasticity., Reyda S, Sohn C, Klebe G, Rall K, Ullmann D, Jakubke HD, Stubbs MT, J Mol Biol. 2003 Jan 31;325(5):963-77. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12527302 12527302]
Reconstructing the binding site of factor Xa in trypsin reveals ligand-induced structural plasticity., Reyda S, Sohn C, Klebe G, Rall K, Ullmann D, Jakubke HD, Stubbs MT, J Mol Biol. 2003 Jan 31;325(5):963-77. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12527302 12527302]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: serine proteinase]]
[[Category: serine proteinase]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:17:50 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:57:34 2008''