1j4h: Difference between revisions

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[[Image:1j4h.jpg|left|200px]]<br /><applet load="1j4h" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1j4h.jpg|left|200px]]
caption="1j4h, resolution 1.8&Aring;" />
 
'''crystal structure analysis of the FKBP12 complexed with 000107 small molecule'''<br />
{{Structure
|PDB= 1j4h |SIZE=350|CAPTION= <scene name='initialview01'>1j4h</scene>, resolution 1.8&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SUB:3-PHENYL-2-{[4-(TOLUENE-4-SULFONYL)-THIOMORPHOLINE-3-CARBONYL]-AMINO}-PROPIONIC ACID ETHYL ESTER'>SUB</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8]
|GENE=
}}
 
'''crystal structure analysis of the FKBP12 complexed with 000107 small molecule'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1J4H is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SUB:'>SUB</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J4H OCA].  
1J4H is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J4H OCA].  


==Reference==
==Reference==
Design and structure-based study of new potential FKBP12 inhibitors., Sun F, Li P, Ding Y, Wang L, Bartlam M, Shu C, Shen B, Jiang H, Li S, Rao Z, Biophys J. 2003 Nov;85(5):3194-201. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=14581219 14581219]
Design and structure-based study of new potential FKBP12 inhibitors., Sun F, Li P, Ding Y, Wang L, Bartlam M, Shu C, Shen B, Jiang H, Li S, Rao Z, Biophys J. 2003 Nov;85(5):3194-201. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14581219 14581219]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Peptidylprolyl isomerase]]
[[Category: Peptidylprolyl isomerase]]
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[[Category: rotamase]]
[[Category: rotamase]]


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