1jcs: Difference between revisions

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[[Image:1jcs.gif|left|200px]]<br /><applet load="1jcs" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1jcs.gif|left|200px]]
caption="1jcs, resolution 2.20&Aring;" />
 
'''CRYSTAL STRUCTURE OF RAT PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH THE PEPTIDE SUBSTRATE TKCVFM AND AN ANALOG OF FARNESYL DIPHOSPHATE'''<br />
{{Structure
|PDB= 1jcs |SIZE=350|CAPTION= <scene name='initialview01'>1jcs</scene>, resolution 2.20&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=FII:[(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC+ACID'>FII</scene> and <scene name='pdbligand=ACY:ACETIC ACID'>ACY</scene>
|ACTIVITY=
|GENE=
}}
 
'''CRYSTAL STRUCTURE OF RAT PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH THE PEPTIDE SUBSTRATE TKCVFM AND AN ANALOG OF FARNESYL DIPHOSPHATE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1JCS is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=FII:'>FII</scene> and <scene name='pdbligand=ACY:'>ACY</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JCS OCA].  
1JCS is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JCS OCA].  


==Reference==
==Reference==
The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics., Long SB, Hancock PJ, Kral AM, Hellinga HW, Beese LS, Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):12948-53. Epub 2001 Oct 30. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11687658 11687658]
The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics., Long SB, Hancock PJ, Kral AM, Hellinga HW, Beese LS, Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):12948-53. Epub 2001 Oct 30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11687658 11687658]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: pft]]
[[Category: pft]]
[[Category: pftase]]
[[Category: pftase]]
[[Category: ras]]
[[Category: ra]]


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